A Case of in utero Transmission of Drug-resistant HIV in the United States

被引：0
|
作者：
Weyland, Cassie [1 ]
Mirani, Gayatri [2 ]
Gillespie, Susan L. [2 ]
Paul, Mary E. [2 ]
机构：
[1] Baylor Coll Med, Internal Med Pediat, PGY 1, Houston, TX 77030 USA
[2] Texas Childrens Hosp, Baylor Coll Med, Sect Immunol Allergy & Retrovirol, Houston, TX 77030 USA
来源：
PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2022年 / 41卷 / 01期
关键词：
perinatal transmission; HIV drug resistance; antiretroviral therapy; FAILURE;
D O I：
10.1097/INF.0000000000003329
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Thanks to the development of antiretroviral drugs and the implementation of routine perinatal prophylaxis, primarily containing zidovudine, modern-day rates of perinatal transmission of HIV are very low in developed countries. We present a case of perinatal transmission of HIV with extensive nucleoside reverse transcriptase inhibitor resistance as a reminder that perinatal transmission of resistance mutations can occur. This case calls for further investigation into the utility of using genotype to determine neonatal prophylaxis in the setting of maternal HIV drug resistance.
引用
收藏
页码：57 / 59
页数：3
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