Tetrahydroxanthones from Mongolian medicinal plant Gentianella amarella ssp acuta

被引：18

作者：

Lu, Shuangxin ^{[1
]}

Tanaka, Naonobu ^{[1
,2
]}

Kawazoe, Kazuyoshi ^{[1
]}

Murakami, Kotaro ^{[3
]}

Damdinjav, Davaadagva ^{[4
]}

Dorjbal, Enkhjargal ^{[4
]}

Kashiwada, Yoshiki ^{[1
]}

机构：

[1] Univ Tokushima, Grad Sch Pharmaceut Sci, Tokushima 7708505, Japan

[2] Univ Tokushima, Grad Sch Biosci & Bioind, Tokushima 7708513, Japan

[3] Sojo Univ, Fac Pharmaceut Sci, Kumamoto 8620082, Japan

[4] Mongolian Natl Univ Med Sci, Sch Pharmaceut Biomed Sci, Ulaanbaatar 14210, Mongolia

来源：

JOURNAL OF NATURAL MEDICINES | 2016年 / 70卷 / 04期

关键词：

Tetrahydroxanthone; Gentianella amarella ssp acuta; Gentianaceae; Amarellins A-F; SWERTIA JAPONICA; XANTHONES; CONSTITUENTS; GLUCOSIDE; ASSIGNMENTS;

D O I：

10.1007/s11418-016-1015-z

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two tetrahydroxanthones, 1,3,5S,8S-tetrahydroxy-5,6,7,8-tetrahydroxanthone (1) and 1,3,5R,8S-tetrahydroxy-5,6,7,8-tetrahydroxanthone (2), and six new tetrahydroxanthone glycosides, amarellins A-F (3-8), were isolated from the aerial parts of a Mongolian medicinal plant Gentianella amarella ssp. acuta (Gentianaceae). The structures of 1-8 were elucidated on the basis of spectroscopic analysis, chemical conversion, and ECD calculation. Amarellins A-C (3-5) were assigned as 8-O-beta-d-glucoside, 8-O-beta-d-xyloside, and 1-O-beta-d-glucoside of 1, respectively, while amarellins D-F (6-8) were elucidated to be 8-O-beta-d-xyloside, 1-O-beta-d-glucoside, and 3-O-beta-d-glucoside of 2, respectively.

引用

页码：780 / 788

页数：9

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