Chemiluminescence and Spectrofluorimetric Methods for Determination of Fluoroquinolones: A Review

Fluoroquinolones are an important and extensively studied group of compounds. Newer generations of fluoroquinolones are being developed to enhance the antimicrobial spectrum and pharmacological properties of these antimicrobials. Various analytical methods including chromatographic, voltametric, titrimetric, potentiometric, spectrophotometric, and so forth have been reported for analysis of these drugs. However luminescence and spectrofluorimetric methods continue to hold much significance as they are simple, economical, and sensitive as compared to most of the other methods. This led us to review the luminescence and spectrofluorimetric methods described for the analysis of this important class of drugs either per se, in dosage forms, or in biological fluids.