Heart failure with mid-range ejection fraction: pro and cons of the new classification of Heart Failure by European Society of Cardiology guidelines

被引：33

作者：

Branca, Luca ^{[1
,2
]}

Sbolli, Marco ^{[1
,2
]}

Metra, Marco ^{[1
,2
]}

Fudim, Marat ^{[3
,4
]}

机构：

[1] Civil Hosp, Cardiothorac Dept, Brescia, Italy

[2] Univ Brescia, Publ Hlth, Radiolo Sci, Dept Med & Surg Special, Brescia, Italy

[3] Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA

[4] Duke Clin Res Inst, Durham, NC USA

来源：

ESC HEART FAILURE | 2020年 / 7卷 / 02期

基金：

美国国家卫生研究院;

关键词：

Heart failure with mid-range ejection fraction; Heart failure with preserved ejection fraction; Heart failure with reduced ejection fraction; Classification; GLOBAL LONGITUDINAL STRAIN; LONG-TERM SURVIVAL; ATRIAL-FIBRILLATION; CARDIOVASCULAR OUTCOMES; CATHETER ABLATION; PROGNOSTIC IMPACT; BORDERLINE; INSIGHTS; SPIRONOLACTONE; 55-PERCENT;

D O I：

10.1002/ehf2.12586

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Currently, the assessment of left ventricular ejection fraction (LVEF) is the cornerstone of the classification of patients with heart failure (HF). The mid-range LVEF (HFmrEF) category was identified in an attempt to uncover specific characteristics of these patients. So far, the analysis of trials, registries, and observational studies have demonstrated that patients with mid-range LVEF belong to a patient cohort with generally intermediate clinical profile as compared with other groups but with a remarkable variety of intrinsic phenotypes. This is due to the limitations of LVEF as the sole criterion to categorize patients with HF and characterize their prognosis, above all when it is >40%. To better define the HFmrEF phenotype, it is reasonable to consider other parameters, such as LVEF changes over time, HF aetiology, co-morbidities, and other imaging parameters. A multiparametric evaluation may contextualize a patient with HFmrEF in a more defined phenotype with a specific prognosis.

引用

页码：381 / 399

页数：19

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