Impact of Maternal Obesity on Fetal Programming of Cardiovascular Disease

被引：58
|
作者：
Roberts, Victoria H. J. [1 ]
Frias, Antonio E. [1 ,2 ]
Grove, Kevin L. [1 ]
机构：
[1] Oregon Natl Primate Res Ctr, Div Diabet Obes & Metab, Beaverton, OR 97006 USA
[2] Oregon Hlth & Sci Univ, Dept Obstet & Gynecol, Portland, OR 97201 USA
来源：
PHYSIOLOGY | 2015年 / 30卷 / 03期
基金：
美国国家卫生研究院;
关键词：
CELL-CYCLE ACTIVITY; BODY-MASS INDEX; BLOOD-PRESSURE; TROPHOBLAST INVASION; NATRIURETIC-PEPTIDE; NONHUMAN PRIMATE; ADIPOSE-TISSUE; RAT MODEL; PREGNANCY; ARTERIAL;
D O I：
10.1152/physiol.00021.2014
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
The in utero environment is a key determinant of long-term health outcomes; poor maternal metabolic state and placental insufficiency are strongly associated with these long-term health risks. Human epidemiological studies link maternal obesity and offspring cardiovascular disease in later life, but mechanistic studies in animal models are limited. Here, we review the literature pertaining to maternal consequences of obesity during pregnancy and the subsequent impact on fetal cardiovascular development.
引用
收藏
页码：224 / 231
页数：8
相关论文
共 50 条
  • [31] Maternal high fat diets: impacts on offspring obesity and epigenetic hypothalamic programming
    Harmancioglu, Beguem
    Kabaran, Seray
    FRONTIERS IN GENETICS, 2023, 14
  • [32] The impact of parity and maternal obesity on the fetal outcomes of a non-selected Lower Saxony population
    Brodowski, Lars
    Rochow, Niels
    Yousuf, Efrah, I
    Kohls, Fabian
    von Kaisenberg, Constantin S.
    Berlage, Silvia
    Voigt, Manfred
    JOURNAL OF PERINATAL MEDICINE, 2022, 50 (02) : 167 - 175
  • [33] Breastfeeding and later maternal risk of hypertension and cardiovascular disease - The role of overall and abdominal obesity
    Kirkegaard, H.
    Bliddal, M.
    Stovring, H.
    Rasmussen, K. M.
    Gunderson, E. P.
    Kober, L.
    Sorensen, T. I. A.
    Nohr, E. A.
    PREVENTIVE MEDICINE, 2018, 114 : 140 - 148
  • [34] Maternal obesity induces fibrosis in fetal myocardium of sheep
    Huang, Yan
    Yan, Xu
    Zhao, Jun X.
    Zhu, Mei J.
    McCormick, Richard J.
    Ford, Stephen P.
    Nathanielsz, Peter W.
    Ren, Jun
    Du, Min
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2010, 299 (06): : E968 - E975
  • [35] Fetal environment and subsequent obesity: a study of maternal smoking
    Power, C
    Jefferis, BJMH
    INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2002, 31 (02) : 413 - 419
  • [36] Maternal Obesity and Detection Rate of Fetal Structural Anomalies
    Hildebrand, Eric
    Gottvall, Tomas
    Blomberg, Marie
    FETAL DIAGNOSIS AND THERAPY, 2013, 33 (04) : 246 - 251
  • [37] Maternal obesity blunts antimicrobial responses in fetal monocytes
    Sureshchandra, Suhas
    Doratt, Brianna M.
    Mendza, Norma
    Varlamov, Oleg
    Rincon, Monica
    Marshall, Nicole E.
    Messaoudi, Ilhem
    ELIFE, 2023, 12
  • [38] Maternal and Fetal Lipid and Adipokine Profiles and Their Association with Obesity
    Solis-Paredes, Mario
    Espino y Sosa, Salvador
    Estrada-Gutierrez, Guadalupe
    Nava-Salazar, Sonia
    Ortega-Castillo, Veronica
    Rodriguez-Bosch, Mario
    Bravo-Flores, Eyerahi
    Espejel-Nunez, Aurora
    Tolentino-Dolores, Maricruz
    Gaona-Estudillo, Rubi
    Martinez-Bautista, Nancy
    Perichart-Perera, Otilia
    INTERNATIONAL JOURNAL OF ENDOCRINOLOGY, 2016, 2016
  • [39] Fetal Programming and the Risk of Noncommunicable Disease
    Fall, Caroline H. D.
    INDIAN JOURNAL OF PEDIATRICS, 2013, 80 : S13 - S20
  • [40] Childhood obesity and cardiovascular disease
    Bridger, Tracey
    PAEDIATRICS & CHILD HEALTH, 2009, 14 (03) : 177 - 182
12345