Synthesis and Intramolecular Cyclization of Substituted 4-(Het)aryl-4-oxo-2-thienylaminobut-2-enoic Acids Containing Nitrile Group in the Thiophene Ring

被引：0
作者：
Gorbunova, I. A. [1 ]
Shipilovskikh, D. A. [2 ]
Rubtsov, A. E. [1 ]
Shipilovskikh, S. A. [1 ,3 ]
机构：
[1] Perm State Univ, Perm 614990, Russia
[2] Perm Natl Res Polytech Univ, Perm 614990, Russia
[3] ITMO Univ, St Petersburg 197101, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2021年 / 91卷 / 09期
关键词：
Gewald thiophenes; 2; 4-dioxobutanoic acids; 3-(thiophen-2-yl)iminofuran-2(3H)-one; CAP-SNATCHING ENDONUCLEASE; IMINOFURANS; RECYCLIZATION; DIKETO ACIDS; ETHYL; DECYCLIZATION; CHEMISTRY; DERIVATIVES; INHIBITORS;
D O I：
10.1134/S1070363221090048
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A method for the synthesis of substituted 4-(het)aryl-4-oxo-2-thienylaminobut-2-enoic acids containing a nitrile substituent in the thiophene ring was proposed. Intramolecular cyclization of the obtained compounds in the presence of propionic anhydride leads to the formation of new substituted 3-thienylimino-3H-furan-2-ones.
引用
收藏
页码：1623 / 1628
页数：6
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