Efficacy and Safety of Long-Acting Reversible Contraception

被引:126
作者
Stoddard, Amy [1 ]
McNicholas, Colleen [1 ]
Peipert, Jeffrey F. [1 ]
机构
[1] Washington Univ, Sch Med, Dept Obstet & Gynecol, Div Clin Res, St Louis, MO 63110 USA
基金
美国国家卫生研究院;
关键词
INTRAUTERINE SYSTEM MIRENA(R); ETONOGESTREL IMPLANT IMPLANON; CLINICAL-PERFORMANCE; LEVONORGESTREL; DEVICES; WOMEN; IUD; EXPERIENCE; PREGNANCY; INSERTION;
D O I
10.2165/11591290-000000000-00000
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Long-acting reversible contraception (LA RC) includes intrauterine devices (IUDs) and the subdermal implant. These methods are the most effective reversible methods of contraception, and have the additional advantages of being long-lasting, convenient, well liked by users and cost effective. Compared with other user-dependent methods that increase the risk of noncompliance-related method failure, LARC methods can bring 'typical use' failure rates more in line with 'perfect use' failure rates. LARC methods are 'forgettable'; they are not dependent on compliance with a pill-taking regimen, remembering to change a patch or ring, or coming back to the clinician for an injection. LARC method failure rates rival that of tubal sterilization at < 1% for IUDs and the subdermal implant. For these reasons, we believe that IUDs and implants should be offered as first-line contraception for most women. This article provides a review of the LARC methods that are currently available in the US, including their effectiveness, advantages, disadvantages and contraindications. Additionally, we dispel myths and misconceptions regarding IUDs, and address the barriers to LARC use.
引用
收藏
页码:969 / 980
页数:12
相关论文
共 56 条
[41]   RATES AND OUTCOMES OF PLANNED PREGNANCY AFTER USE OF NORPLANT CAPSULES, NORPLANT-II RODS, OR LEVONORGESTREL-RELEASING OR COPPER TCU-380AG INTRAUTERINE CONTRACEPTIVE DEVICES [J].
SIVIN, I ;
STERN, J ;
DIAZ, S ;
PAVEZ, M ;
ALVAREZ, F ;
BRACHE, V ;
MISHELL, DR ;
LACARRA, M ;
MCCARTHY, T ;
HOLMA, P ;
DARNEY, P ;
KLAISLE, C ;
OLSSON, SE ;
ODLIND, V .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1992, 166 (04) :1208-1213
[42]   PROLONGED INTRAUTERINE CONTRACEPTION - A 7-YEAR RANDOMIZED STUDY OF THE LEVONORGESTREL 20 MCG/DAY (LNG-20) AND THE COPPER T380 AG IUDS [J].
SIVIN, I ;
STERN, J ;
COUTINHO, E ;
MATTOS, CER ;
ELMAHGOUB, S ;
DIAZ, S ;
PAVEZ, M ;
ALVAREZ, F ;
BRACHE, V ;
THEVENIN, F ;
DIAZ, J ;
FAUNDES, A ;
DIAZ, MM ;
MCCARTHY, T ;
MISHELL, DR ;
SHOUPE, D .
CONTRACEPTION, 1991, 44 (05) :473-480
[43]   INFLUENCE OF AN INTRAUTERINE-DEVICE ON THE COURSE OF AN ACUTE SALPINGITIS [J].
SODERBERG, G ;
LINDGREN, S .
CONTRACEPTION, 1981, 24 (02) :137-143
[44]  
Sonfield A., 2007, Guttmacher policy review, V10, P19
[45]   CONTRACEPTIVES AND ACUTE SALPINGITIS [J].
SVENSSON, L ;
WESTROM, L ;
MARDH, PA .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1984, 251 (19) :2553-2555
[46]   DALKON-SHIELD CONTROVERSY - STRUCTURAL AND BACTERIOLOGICAL STUDIES OF IUD-TAILS [J].
TATUM, HJ ;
SCHMIDT, FH ;
PHILLIPS, D ;
MCCARTY, M ;
OLEARY, WM .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1975, 231 (07) :711-717
[48]   Ultrasonographic features of the endometrium and the ovaries in women on etonogestrel implant [J].
Van Den Bosch, T ;
Donders, GGG ;
Riphagen, I ;
Debois, P ;
Ameye, L ;
De Brabanter, J ;
Van Huffel, S ;
Van Schoubroeck, D ;
Timmerman, D .
ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 2002, 20 (04) :377-380
[49]   FERTILITY AFTER STOPPING USE OF INTRAUTERINE CONTRACEPTIVE DEVICE [J].
VESSEY, MP ;
LAWLESS, M ;
MCPHERSON, K ;
YEATES, D .
BRITISH MEDICAL JOURNAL, 1983, 286 (6359) :106-106
[50]   Randomised controlled trial of prophylactic antibiotics before insertion of intrauterine devices [J].
Walsh, T ;
Grimes, D ;
Frezieres, R ;
Nelson, A ;
Bernstein, L ;
Coulson, A ;
Bernstein, G .
LANCET, 1998, 351 (9108) :1005-1008