A rare case of primary gastric plasmacytoma: An unforeseen surprise

被引:12
作者
Krishnamoorthy, Navin [1 ]
Bal, Munita M. [1 ]
Ramadwar, Mukta [1 ]
Deodhar, Kedar [1 ]
Mohandas, K. M. [2 ]
机构
[1] Tata Mem Hosp, Dept Pathol, Bombay 400012, Maharashtra, India
[2] Tata Mem Hosp, Dept Digest Dis, Bombay 400012, Maharashtra, India
关键词
Differential diagnosis; immunohistochemistry; primary gastric plasmacytoma; EXTRAMEDULLARY PLASMACYTOMA; SOLITARY PLASMACYTOMA; HELICOBACTER-PYLORI; ERADICATION; BONE;
D O I
10.4103/0973-1482.77067
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Primary plasmacytoma of the gastrointestinal tract is a rare entity. We report a case of a primary gastric plasmacytoma in a 57-year-old man who presented with upper-gastrointestinal bleeding. Endoscopy showed a nodular gastric mass with central umblication. Histological examination of the gastrectomy specimen revealed a monoclonal lambda-chain extramedullary plasmacytoma. Further staging was found to be negative for multiple myeloma. As other more common pathologic processes at this site may also be endowed with numerous plasma cells, awareness of this entity and distinction using immunohistochemistry are extremely crucial. Because systemic disease ultimately develops in many patients with localized plasmacytoma, such patients should be followed closely for the appearance of clinical, biochemical, and roentgenologic evidence of multiple myeloma.
引用
收藏
页码:549 / 551
页数:3
相关论文
共 9 条
[1]  
Alexiou C, 1999, CANCER, V85, P2305, DOI 10.1002/(SICI)1097-0142(19990601)85:11<2305::AID-CNCR2>3.3.CO
[2]  
2-V
[3]   Solitary plasmacytoma of bone and extramedullary plasmacytoma [J].
Dimopoulos, MA ;
Kiamouris, C ;
Moulopoulos, LA .
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 1999, 13 (06) :1249-+
[4]  
Galieni P, 2000, HAEMATOLOGICA, V85, P47
[5]   A case of gastric plasmacytoma associated with Helicobacter pylori infection:: improvement of abnormal endoscopic and EUS findings after H pylori eradication [J].
Kato, K ;
Sugitani, M ;
Nagata, T ;
Nishinarita, S ;
Kawamura, F ;
Takahashi, Y ;
Ishii, Y ;
Kawamura, Y ;
Komuro, S ;
Yanai, M ;
Nemoto, N ;
Arakawa, Y .
GASTROINTESTINAL ENDOSCOPY, 2001, 53 (03) :352-355
[6]   Solitary plasmacytoma of bone and soft tissues [J].
Mendenhall, WM ;
Mendenhall, CM ;
Mendenhall, NP .
AMERICAN JOURNAL OF OTOLARYNGOLOGY, 2003, 24 (06) :395-399
[7]   Primary gastric plasmacytoma at an early stage:: Unremarkable effect of eradication of Helicobacter pylori [J].
Minami, T ;
Nishimura, S ;
Asagoe, K ;
Tsujimura, T ;
Yamamoto, T ;
Kondo, S ;
Ohmori, Y ;
Kanayama, S .
INTERNAL MEDICINE, 2003, 42 (04) :370-372
[8]   Plasma cell neoplasms - Review of disease progression and report of a new variant [J].
Nolan, KD ;
Mone, MC ;
Nelson, EW .
SURGICAL ONCOLOGY-OXFORD, 2005, 14 (02) :85-90
[9]   GASTRIC INVOLVEMENT WITH EXCAVATED PLASMACYTOMA - CASE-REPORT AND REVIEW OF ENDOSCOPIC CRITERIA [J].
SLOYER, A ;
KATZ, S ;
JAVORS, FACPB ;
KAHN, E .
ENDOSCOPY, 1988, 20 (05) :267-269