Gut microbiota and stroke

被引：20

作者：

Tan, Benjamin Y. Q. ^{[1
,2
]}

Paliwal, Prakash R. ^{[1
]}

Sharma, Vijay K. ^{[1
,2
]}

机构：

[1] Natl Univ Hlth Syst, Div Neurol, Dept Med, Singapore, Singapore

[2] Yong Loo Lin Sch Med Singapore, Dept Med, Singapore, Singapore

来源：

ANNALS OF INDIAN ACADEMY OF NEUROLOGY | 2020年 / 23卷 / 02期

关键词：

Gut dysbiosis; gut microbiota; stroke; TRIMETHYLAMINE-N-OXIDE; METABOLISM; INJURY; PHOSPHATIDYLCHOLINE; DYSBIOSIS; MICE;

D O I：

10.4103/aian.AIAN_483_19

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Ischemic stroke remains a significant health problem, which is expected to increase owing to an aging population. A considerable proportion of stroke patients suffer from gastrointestinal complications, including dysphagia, gastrointestinal hemorrhage, and constipation. Often, these complications adversely affect stroke outcomes. Recent research postulates the role of "brain-gut axis" in causing gut microbiota dysbiosis and various complications and outcomes. In this review, we present our current understanding about the interaction between commensal gut microbiome and brain in determining the course of stroke.

引用

页码：155 / 158

页数：4

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