Targeted treatment for fragile X syndrome: results of a randomized controlled phase II trial of arbaclofen

被引:0
|
作者
Hagerman, Randi [1 ,2 ]
Rathmell, Barbara [3 ]
Wang, Lulu [1 ,2 ]
Carpenter, Randy [3 ]
Wang, Paul [3 ]
Berry-Kravis, Elizabeth [4 ]
机构
[1] UC Davis Med Ctr, MIND Inst, Sacramento, CA USA
[2] UC Davis Med Ctr, Dept Pediat, Sacramento, CA USA
[3] Seaside Therapeut, Boston, MA USA
[4] Rush Univ, Med Ctr, Dept Neurol, Chicago, IL 60612 USA
关键词
fragile X syndrome; targeted treatments; GABA; arbaclofen;
D O I
暂无
中图分类号
G76 [特殊教育];
学科分类号
040109 ;
摘要
引用
收藏
页码:884 / 884
页数:1
相关论文
共 50 条
  • [41] Lithium: A Promising Treatment for Fragile X Syndrome
    Liu, Zhonghua
    Smith, Carolyn Beebe
    ACS CHEMICAL NEUROSCIENCE, 2014, 5 (06): : 477 - 483
  • [42] A phase 1, randomized double-blind, placebo controlled trial to evaluate safety and efficacy of epigallocatechin-3-gallate and cognitive training in adults with Fragile X syndrome
    de la Torre, Rafael
    de Sola, Susana
    Farre, Magi
    Xicota, Laura
    Cuenca-Royo, Aida
    Rodriguez, Joan
    Leon, Alba
    Langohr, Klaus
    Gomis-Gonzalez, Maria
    Hernandez, Gimena
    Esteba, Susanna
    del Hoyo, Laura
    Sanchez-Gutierrez, Judit
    Jose Cortes, Maria
    Ozaita, Andres
    Maria Espadaler, Josep
    Novell, Ramon
    Martinez-Leal, Rafael
    Mila, Montserrat
    Dierssen, Mara
    CLINICAL NUTRITION, 2020, 39 (02) : 378 - 387
  • [43] Controlled trial of lovastatin combined with an open-label treatment of a parent-implemented language intervention in youth with fragile X syndrome
    Angela John Thurman
    Laura A. Potter
    Kyoungmi Kim
    Flora Tassone
    Amy Banasik
    Sarah Nelson Potter
    Lauren Bullard
    Vivian Nguyen
    Andrea McDuffie
    Randi Hagerman
    Leonard Abbeduto
    Journal of Neurodevelopmental Disorders, 2020, 12
  • [44] Controlled trial of lovastatin combined with an open-label treatment of a parent-implemented language intervention in youth with fragile X syndrome
    Thurman, Angela John
    Potter, Laura A.
    Kim, Kyoungmi
    Tassone, Flora
    Banasik, Amy
    Potter, Sarah Nelson
    Bullard, Lauren
    Nguyen, Vivian
    McDuffie, Andrea
    Hagerman, Randi
    Abbeduto, Leonard
    JOURNAL OF NEURODEVELOPMENTAL DISORDERS, 2020, 12 (01)
  • [45] Overlapping Molecular Pathways Leading to Autism Spectrum Disorders, Fragile X Syndrome, and Targeted Treatments
    Salcedo-Arellano, Maria Jimena
    Cabal-Herrera, Ana Maria
    Punatar, Ruchi Harendra
    Clark, Courtney Jessica
    Romney, Christopher Allen
    Hagerman, Randi J.
    NEUROTHERAPEUTICS, 2021, 18 (01) : 265 - 283
  • [46] Open-label treatment trial of lithium to target the underlying defect in fragile X syndrome
    Berry-Kravis, Elizabeth
    Sumis, Allison
    Hervey, Crystal
    Nelson, Michael
    Porges, Stephen W.
    Weng, Ning
    Weiler, Ivan Jeanne
    Greenough, William T.
    JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS, 2008, 29 (04) : 293 - 302
  • [47] Overlapping Molecular Pathways Leading to Autism Spectrum Disorders, Fragile X Syndrome, and Targeted Treatments
    Maria Jimena Salcedo-Arellano
    Ana Maria Cabal-Herrera
    Ruchi Harendra Punatar
    Courtney Jessica Clark
    Christopher Allen Romney
    Randi J Hagerman
    Neurotherapeutics, 2021, 18 : 265 - 283
  • [48] Serotonin dysregulation in Fragile X Syndrome: implications for treatment
    Hanson, Alicia C.
    Hagerman, Randi J.
    INTRACTABLE & RARE DISEASES RESEARCH, 2014, 3 (04) : 110 - 117
  • [49] Caregiver Preferences for the Treatment of Males with Fragile X Syndrome
    Cross, James
    Yang, Jui-Chen
    Johnson, F. Reed
    Quiroz, Jorge
    Dunn, Judith
    Raspa, Melissa
    Bailey, Donald B., Jr.
    JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS, 2016, 37 (01) : 71 - 79
  • [50] Emerging pharmacologic treatment options for fragile X syndrome
    Schaefer, Tori L.
    Davenport, Matthew H.
    Erickson, Craig A.
    APPLICATION OF CLINICAL GENETICS, 2015, 8 : 75 - 93