Dendrimer nanoplatforms for veterinary medicine applications: A concise overview

被引:9
作者
Mignani, Serge [1 ,2 ]
Shi, Xiangyang [2 ,3 ]
Rodrigues, Joao [2 ,4 ]
Tomas, Helena [2 ]
Majoral, Jean-Pierre [5 ,6 ]
机构
[1] Univ Paris 05, PRES Sorbonne Paris Cite, CNRS UMR 860, Lab Chim & Biochim Pharmacol & Toxicol, 45 Rue St Peres, F-75006 Paris, France
[2] Univ Madeira, CQM Ctr Quim Madeira, MMRG, Campus Penteada, P-9020105 Funchal, Portugal
[3] Donghua Univ, Coll Chem Chem Engn & Biotechnol, Shanghai 201620, Peoples R China
[4] Northwestern Polytech Univ, Ctr Nano Energy Mat, Sch Mat Sci & Engn, Xian 710072, Peoples R China
[5] CNRS, Lab Chim Coordinat, 205 Route Narbonne, F-31077 Toulouse 4, France
[6] Univ Toulouse, 118 Route Narbonne, F-31077 Toulouse 4, France
关键词
Nanomedicine; Dendrimers; Veterinary medicine; Foot and mouth disease; Swine fever; Hypothermic circulatory arrest; H9N2 avian influenza; HYPOTHERMIC CIRCULATORY ARREST; MOUTH-DISEASE VIRUS; SWINE-FEVER VIRUS; PHOSPHORUS DENDRIMERS; BRAIN-INJURY; PROTECTIVE IMMUNITY; VACCINE ADJUVANTS; CANINE MODEL; CITRIC-ACID; NANOMEDICINE;
D O I
10.1016/j.drudis.2022.01.001
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Within the nanoparticle (NP) space, dendrimers are becoming increasingly important in the field of nanomedicine, not only to treat human diseases, but also in veterinary medicine, which represents a new therapeutic approach. Major applications include using dendrimers to tackle highly contagious foot-and-mouth disease virus (FMDV) and swine fever virus (SFV) in pigs, FMDV in cattle, hypothermic circulatory arrest (HCA) in dogs, rabies, and H9N2 avian influenza virus in chickens. As we review here, intramuscular (im) subcutaneous (sc), intravenous (iv), and intraperitoneal (ip) routes of administration can be used for the successful application of dendrimers in animals.
引用
收藏
页码:1251 / 1260
页数:10
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