Current status of the development of an artificial salivary gland

被引：44

作者：

Aframian, Doron J. ^{[1
]}

Palmon, Aaron ^{[2
]}

机构：

[1] Hebrew Univ Jerusalem, Hadassah Sch Dent Med, Salivary Gland Clin, Dept Oral Med, IL-91120 Jerusalem, Israel

[2] Hebrew Univ Jerusalem, Hadassah Sch Dent Med, Fac Med Dent, Inst Dent Sci, IL-91120 Jerusalem, Israel

来源：

TISSUE ENGINEERING PART B-REVIEWS | 2008年 / 14卷 / 02期

关键词：

D O I：

10.1089/ten.teb.2008.0044

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Salivary glands (SGs) secrete more than half a liter of saliva daily. Saliva has many functions in maintaining the normal homeostasis of the oral cavity. Several causes underlie salivary impairment, where irradiation therapy to head and neck cancer patients is one of the most debilitating causes leading to considerable decrease in the patients' quality of life. In the last decade, others and we have focused on implementing tissue engineering principles combined with gene transfer and stem cell methodologies to develop an artificial SG device. This manuscript provides an overview of the current status of engineering an artificial SG.

引用

页码：187 / 198

页数：12

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