Non-vitamin K antagonist oral anticoagulants for heart diseases

被引：0

作者：

Kondratieva, T. B. ^{[1
]}

Popova, L. V. ^{[1
]}

Bokarev, I. N. ^{[1
]}

机构：

[1] IM Sechenov First Moscow State Med Univ, Minist Hlth Russia, Moscow, Russia

来源：

TERAPEVTICHESKII ARKHIV | 2017年 / 89卷 / 09期

关键词：

non-vitamin K antagonist oral anticoagulants; warfarin; stroke prevention; venous thromboembolism; left atrial thrombus; atrial fibrillation; heart valve diseases; ATRIAL-FIBRILLATION PATIENTS; ANTITHROMBOTIC THERAPY; PREVENT THROMBOEMBOLISM; 1ST-LINE AGENTS; WARFARIN; STROKE; EFFICACY; FAILURE; RISK; ASSOCIATION;

D O I：

10.17116/terarkh2017899120-127

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Non-vitamin K antagonist oral anticoagulants (NOACs) are highly effective drugs that prevent venous thrombosis and stroke in atrial fibrillation. Their use has difficulties that are associated with the need for laboratory control and with the influence of many factors on the activity of these medications. The emerged direct oral anticoagulants have some advantages over NOACs. Nevertheless, there are a number of pathological conditions, in which NOACs remain first-line drugs. These include prosthetic mechanical heart valves, a glomerular filtration rate less than 60 mL/min/1.73 m(2), and left atrial thrombus.

引用

页码：120 / 127

页数：8

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