Singlet Oxygen and Free Radical Reactions of Retinoids and Carotenoids-A Review

被引：115

作者：

Edge, Ruth ^{[1
]}

Truscott, T. George ^{[2
]}

机构：

[1] Univ Manchester, Dalton Cumbrian Facil, Westlakes Sci & Technol Pk, Moor Row CA24 3HA, Cumbria, England

[2] Keele Univ, Sch Chem & Phys Sci, Lennard Jones Bldg, Keele ST5 5BG, Staffs, England

来源：

ANTIOXIDANTS | 2018年 / 7卷 / 01期

关键词：

carotenoids; xanthophylls; retinoids; lycopene; pro-/anti-oxidants; singlet oxygen; neutral free radicals; radical cations/anions; hydroxyl radical; hydrogen abstraction; LASER FLASH-PHOTOLYSIS; ANTIOXIDANT BETA-CAROTENE; AQUEOUS TRITON X-100; DIETARY CAROTENOIDS; LIPID-PEROXIDATION; ELECTRON-TRANSFER; MOLECULAR-OXYGEN; NEUTRAL RADICALS; ALPHA-TOCOPHEROL; PHOTOSYSTEM-II;

D O I：

10.3390/antiox7010005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We report on studies of reactions of singlet oxygen with carotenoids and retinoids and a range of free radical studies on carotenoids and retinoids with emphasis on recent work, dietary carotenoids and the role of oxygen in biological processes. Many previous reviews are cited and updated together with new data not previously reviewed. The review does not deal with computational studies but the emphasis is on laboratory-based results. We contrast the ease of study of both singlet oxygen and polyene radical cations compared to neutral radicals. Of particular interest is the switch from anti- to pro-oxidant behavior of a carotenoid with change of oxygen concentration: results for lycopene in a cellular model system show total protection of the human cells studied at zero oxygen concentration, but zero protection at 100% oxygen concentration.

引用

页数：16

共 80 条

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