The kidney in tuberous sclerosis: Manifestations and molecular genetic mechanisms

被引：0
作者：
Sampson, JR
机构：
来源：
NEPHROLOGY DIALYSIS TRANSPLANTATION | 1996年 / 11卷
关键词：
kidney; tuberous sclerosis;
D O I：
暂无
中图分类号：
R3 [基础医学]; R4 [临床医学];
学科分类号：
1001 ; 1002 ; 100602 ;
摘要：
Renal involvement is common in tuberous sclerosis. Angiomyolipomas and cysts are found in similar to 50 and 30% of patients respectively, and often occur together. Tuberous sclerosis also appears to be associated with a small but increased risk of renal cell carcinoma. Recent studies have begun to elucidate the molecular genetic mechanisms underlying the renal manifestations of this systemic autosomal dominant disorder.
引用
收藏
页码：34 / 37
页数：4
相关论文
共 40 条
[1]   TUBEROUS SCLEROSIS WITH ANGIOMYOLIPOMA AND METASTASIZED HYPERNEPHROMA [J].
AHUJA, S ;
LOFFLER, W ;
WEGENER, OH ;
ERNST, H .
UROLOGY, 1986, 28 (05) :413-419
[2]   OUTCOME OF PATIENTS WITH TUBEROUS SCLEROSIS AFTER RENAL-TRANSPLANTATION [J].
BALLIGAND, JL ;
PIRSON, Y ;
SQUIFFLET, JP ;
COSYNS, JP ;
ALEXANDRE, GPG ;
DESTRIHOU, CV .
TRANSPLANTATION, 1990, 49 (03) :515-518
[3]   RENAL CYSTIC-DISEASE IN THE TUBEROUS SCLEROSIS COMPLEX [J].
BERNSTEIN, J .
PEDIATRIC NEPHROLOGY, 1993, 7 (04) :490-495
[4]   PREOPERATIVE DIAGNOSIS OF RENAL ANGIOMYOLIPOMA - FINE-NEEDLE ASPIRATION CYTOLOGY AND IMMUNOCYTOCHEMICAL CHARACTERIZATION [J].
BONZANINI, M ;
PEA, M ;
MARTIGNONI, G ;
ZAMBONI, G ;
CAPELLI, P ;
BERNARDELLO, F ;
BONETTI, F .
PATHOLOGY, 1994, 26 (02) :170-175
[5]   DELETION OF THE TSC2 AND PKD1 GENES ASSOCIATED WITH SEVERE INFANTILE POLYCYSTIC KIDNEY-DISEASE - A CONTIGUOUS GENE SYNDROME [J].
BROOKCARTER, PT ;
PERAL, B ;
WARD, CJ ;
THOMPSON, P ;
HUGHES, J ;
MAHESHWAR, MM ;
NELLIST, M ;
GAMBLE, V ;
HARRIS, PC ;
SAMPSON, JR .
NATURE GENETICS, 1994, 8 (04) :328-332
[6]   BENIGN RENAL ANGIOMYOLIPOMA WITH REGIONAL LYMPH-NODE INVOLVEMENT [J].
BUSCH, FM ;
BARK, CJ ;
CLYDE, HR .
JOURNAL OF UROLOGY, 1976, 116 (06) :715-717
[7]   9Q34 LOSS OF HETEROZYGOSITY IN A TUBEROUS SCLEROSIS ASTROCYTOMA SUGGESTS A GROWTH SUPPRESSOR-LIKE ACTIVITY ALSO FOR THE TSC1 GENE [J].
CARBONARA, C ;
LONGA, L ;
GROSSO, E ;
BORRONE, C ;
GARRE, MG ;
BRISIGOTTI, M ;
MIGONE, N .
HUMAN MOLECULAR GENETICS, 1994, 3 (10) :1829-1832
[8]   PULMONARY TUBEROUS SCLEROSIS [J].
CASTRO, M ;
SHEPHERD, CW ;
GOMEZ, MR ;
LIE, JT ;
RYU, JH .
CHEST, 1995, 107 (01) :189-195
[9]   RENAL INVOLVEMENT IN TUBEROUS SCLEROSIS [J].
CHONKO, AM ;
WEISS, SM ;
STEIN, JH ;
FERRIS, TF .
AMERICAN JOURNAL OF MEDICINE, 1974, 56 (01) :124-132
[10]   POLYCYSTIC KIDNEY-DISEASE IN THE 1ST YEAR OF LIFE [J].
COLE, BR ;
CONLEY, SB ;
STAPLETON, FB .
JOURNAL OF PEDIATRICS, 1987, 111 (05) :693-699
1234