A Model for Red Blood Cells in Simulations of Large-scale Blood Flows

被引:33
作者
Melchionna, Simone [1 ]
机构
[1] CNR, IPCF, I-00185 Rome, Italy
关键词
hemodynamics; kinetic modeling; Lattice Boltzmann; red blood cells; LATTICE-BOLTZMANN; MECHANICS; RHEOLOGY;
D O I
10.1002/mats.201100012
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Red blood cells (RBCs) are an essential component of blood. A method to include the particulate nature of blood is introduced here with the goal of studying circulation in large-scale realistic vessels. The method uses a combination of the Lattice Boltzmann method (LBM) to account for the plasma motion, and a modified molecular dynamics scheme for the cellular motion. Numerical results illustrate the quality of the model in reproducing known rheological properties of blood as much as revealing the effect of RBC structuring on the wall shear stress, with consequences on the development of cardiovascular diseases.
引用
收藏
页码:548 / 561
页数:14
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