Self-Disorders and Clinical High Risk for Psychosis: An Empirical Study in Help-Seeking Youth Attending Community Mental Health Facilities

被引：51

作者：

Raballo, Andrea ^{[1
,2
]}

Pappagallo, Elena ^{[3
,4
]}

Dell' Erba, Alice ^{[4
]}

Lo Cascio, Nella ^{[3
,5
]}

Patane', Martina ^{[3
]}

Gebhardt, Eva ^{[6
]}

Boldrini, Tommaso ^{[7
]}

Terzariol, Laura ^{[4
]}

Angelone, Massimiliano ^{[3
]}

Trisolini, Alberto ^{[4
]}

Girardi, Paolo ^{[6
]}

Nastro, Paolo Fiori ^{[3
]}

机构：

[1] Univ Oslo, Div Mental Hlth & Addict, KG Jebsen Ctr Psychosis Res, NORMENT, Oslo, Norway

[2] Diakonhjemmet Hosp, Oslo, Norway

[3] Sapienza Univ Rome, Dept Neurol & Psychiat, Rome, Italy

[4] Viterbo Hlth Trust, Dept Mental Hlth, Viterbo, Italy

[5] IRCCS, Bambino Gesu Childrens Hosp, Dept Neurosci, Rome, Italy

[6] Sapienza Univ Rome, St Andrea Hosp, Fac Med & Psychol, Neurosci Mental Hlth & Sensory Funct NESMOS Dept, Rome, Italy

[7] Rome E Hlth Trust, Dept Mental Hlth, Rome, Italy

来源：

SCHIZOPHRENIA BULLETIN | 2016年 / 42卷 / 04期

关键词：

psychosis; prodrome; clinical high risk; self; subjective experience; basic symptoms; positive symptoms; ULTRA-HIGH RISK; SCHIZOPHRENIA-SPECTRUM; INTERRATER RELIABILITY; 1ST-EPISODE PSYCHOSIS; SUBJECTIVE EXPERIENCE; FOLLOW-UP; PREDICTION; VALIDITY; DISTURBANCE; POPULATION;

D O I：

10.1093/schbul/sbv223

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Anomalous subjective experiences involving an alteration of the basic sense of self (ie, Self-disorder [SD]) are emerging as a core marker of schizophrenia spectrum disorders with potential impact on current early detection strategies as well. In this study, we wished to field-test the prevalence of SD in a clinical sample of adolescent/young adult help-seekers at putative risk for psychosis attending standard community mental health facilities in Italy. Participants (n = 47), aged between 14 and 25, underwent extensive psychopathological evaluations with current semi-structured tools to assess Clinical High Risk (CHR) state (ie, Structured Interview for Prodromal Syndromes/Scale of Prodromal Symptoms [SIPS/SOPS], Schizophrenia Proneness Instrument-Adult/Child and Youth [SPI-A/CY]). SD aggregated in CHR subjects as compared to the non-CHR and revealed substantial association with sub-psychotic symptoms (SIPS), subjective experience of cognitive and cognitive-perceptual vulnerability (basic symptoms) and functional level (Global Assessment of functioning). Moreover, a combination of the 2 approaches (ie, CHR plus SD) enabled further "closing-in" on a subgroup of CHR with lower global functioning. The results confirm SD's relevance for the early profiling of youths at potential high risk for psychosis.

引用

页码：926 / 932

页数：7

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