A seminaphthofluorescein-based fluorescent chemodosimeter for the highly selective detection of cysteine

被引:118
作者
Yang, Xiaofeng [1 ,2 ]
Guo, Yixing [1 ]
Strongin, Robert M. [1 ]
机构
[1] Portland State Univ, Dept Chem, Portland, OR 97201 USA
[2] NW Univ Xian, Coll Chem & Mat Sci, Inst Analyt Sci, Key Lab Synthet & Nat Funct Mol Chem,Minist Educ, Xian 710069, Peoples R China
基金
美国国家卫生研究院;
关键词
HOMOCYSTEINE; THIOLS; PROBE; PLASMA;
D O I
10.1039/c2ob25178g
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A fluorescent chemodosimeter for cysteine detection was developed based on a tandem conjugate addition and intramolecular cyclization reaction. The method exhibited an excellent selectivity for cysteine over other biothiols such as homocysteine and glutathione.
引用
收藏
页码:2739 / 2741
页数:3
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