LabPET II, an APD-based PET Detector Module with Counting CT Imaging Capability

被引:0
|
作者
Bergeron, Melanie [1 ]
Thibaudeau, Christian [1 ,3 ]
Cadorette, Jules [1 ]
Pepin, Catherine M. [1 ]
Tetrault, Marc-Andre [3 ]
Davies, Murray [2 ]
Dautet, Henri [2 ]
Deschamps, Pierre [2 ]
Fontaine, Rejean [3 ]
Lecomte, Roger [1 ]
机构
[1] Univ Sherbrooke, Sherbrooke Mol Imaging Ctr, Sherbrooke, PQ J1K 2R1, Canada
[2] Excelitas Technol, Quebec City, PQ, Canada
[3] Univ Sherbrooke, Dept Elect & Comp Engn, Sherbrooke, PQ J1K 2R1, Canada
来源
2011 IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE (NSS/MIC) | 2011年
基金
加拿大自然科学与工程研究理事会; 加拿大健康研究院;
关键词
D O I
暂无
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
CT imaging is currently the standard modality to provide anatomical reference in PET molecular imaging. Since both PET and CT rely on detecting radiation to generate images, it would make sense to use the same detection system for data acquisition. Merging PET and CT hardware imposes stringent requirements on detectors, including wide dynamic range with high signal-to-noise ratio for good energy resolution in both modalities, high pixellisation for high spatial resolution, and very high count rate capabilities. The APD-based LabPET II module is proposed as the building block for a truly combined PET/CT scanner. The module is made of two 4 x 8 APD pixel monolithic arrays mounted side by side unto a custom ceramic holder, with each element having an active area of 1.1 x 1.1 mm(2) at a 1.2 mm pitch, coupled to a 12-mm high LYSO scintillator block array. While a previous version of the module was made of pyramidal shaped crystals (1.35 x 1.35 / 1.2 x 1.2 mm(2), top/bottom), a recent version was designed with a simpler rectangular geometry (1.2 x 1.2 mm(2)), better reflective material optimizing the shift of refractive index at crystal interface, and enhanced APD quantum efficiency to improve intrinsic detector performance. Mean energy resolution was improved to 20 +/- 1 % (formerly 24 +/- 1%) at 511 keV and to 41 +/- 4% (formerly 48 +/- 3%) at 60 keV. These intrinsic detector performance characteristics make the LabPET II module suitable for counting CT imaging with efficient energy discrimination. Initial phantom images obtained from a CT test bench demonstrated excellent contrast linearity as a function of material density and spatial resolution of 0.61 mm FWHM / 1.1 mm FWTM, corresponding to 1.3 lp/mm at MTF10% / 0.73 lp/mm at MTF50%, which allowed 0.75 mm air holes in an Ultra Micro resolution phantom to be clearly distinguished.
引用
收藏
页码:3543 / 3547
页数:5
相关论文
共 50 条
  • [1] LabPET II, an APD-based Detector Module with PET and Counting CT Imaging Capabilities
    Bergeron, Melanie
    Thibaudeau, Christian
    Cadorette, Jules
    Tetrault, Marc-Andre
    Pepin, Catherine M.
    Clerk-Lamalice, Julien
    Loignon-Houle, Francis
    Davies, Murray
    Dautet, Henri
    Deschamps, Pierre
    Fontaine, Rejean
    Lecomte, Roger
    IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2015, 62 (03) : 756 - 765
  • [2] Imaging Performance of the LabPET™ APD-based Digital PET Scanner
    Bergeron, Melanie
    Cadorette, Jules
    Beaudoin, Jean-Francois
    Tetrault, Marc-Andre
    Viscogliosi, Nicolas
    Selivanov, Vitali
    Lepage, Martin D.
    Robert, Ghislain
    Norenberg, Jeffrey P.
    Fontaine, Rejean
    Lecomte, Roger
    2008 IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE (2008 NSS/MIC), VOLS 1-9, 2009, : 3116 - +
  • [3] LabPET II Pixelated APD-Based PET Scanner for High-Resolution Preclinical Imaging
    Lecomte, Roger
    Arpin, Louis
    Beaudoin, Jean-Francois
    Bergeron, Melanie
    Bouchard, Jonathan
    Bouziri, Haithem
    Cadorette, Jules
    Gaudin, Emilie
    Jurgensen, Nadia
    Koua, Konin Calliste
    Trepanier, Pierre-Yves Lauzier
    Leroux, Jean-Daniel
    Loignon-Houle, Francis
    Njejimana, Larissa
    Paille, Maxime
    Paulin, Caroline
    Pepin, Catherine
    Pratte, Jean-Francois
    Samson, Arnaud
    Thibaudeau, Christian
    Viscogliosi, Nicolas
    Fontaine, Rejean
    MEDICAL PHYSICS, 2016, 43 (08) : 4935 - 4935
  • [4] LabPET II, a Novel 64-channel APD-based PET Detector Module with Individual Pixel Readout Achieving Submillimetric Spatial Resolution
    Berard, Philippe
    Bergeron, Melanie
    Pepin, Catherine M.
    Cadorette, Jules
    Tetrault, Marc-Andre
    Viscogliosi, Nicolas
    Fontaine, Rejean
    Dautet, Henri
    Davies, Murray
    Deschamps, Pierre
    Lecomte, Roger
    2008 IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE (2008 NSS/MIC), VOLS 1-9, 2009, : 4730 - +
  • [5] APD-based PET detector for simultaneous PET/MR imaging
    Grazioso, Ronald
    Zhang, Nan
    Corbeil, James
    Schmand, Matthias
    Ladebeck, Ralf
    Vester, Markus
    Schnur, Guenter
    Renz, Wolfgang
    Fischer, Hubertus
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2006, 569 (02): : 301 - 305
  • [6] Performance evaluation of the LabPET™ APD-based digital PET scanner
    Bergeron, Melanie
    Cadorette, Jules
    Beaudoin, Jean-Francois
    Rousseau, Jacques A.
    Dumoulin, Marc
    Lepage, Martin D.
    Robert, Ghislain
    Selivanov, Vitali
    Tetrault, Marc-Andre
    Viscogliosi, Nicolas
    Dumouchel, Tyler
    Thorn, Stephanie
    DaSilva, Jean
    deKemp, Robert A.
    Norenberg, Jeffrey P.
    Fontaine, Rejean
    Lecomte, Roger
    2007 IEEE NUCLEAR SCIENCE SYMPOSIUM CONFERENCE RECORD, VOLS 1-11, 2007, : 4185 - +
  • [7] Performance Evaluation of the LabPET APD-Based Digital PET Scanner
    Bergeron, Melanie
    Cadorette, Jules
    Beaudoin, Jean-Francois
    Lepage, Martin D.
    Robert, Ghislain
    Selivanov, Vitali
    Tetrault, Marc-Andre
    Viscogliosi, Nicolas
    Norenberg, Jeffrey P.
    Fontaine, Rejean
    Lecomte, Roger
    IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2009, 56 (01) : 10 - 16
  • [8] Novel APD-based detector module for multi-modality PET/SPECT/CT scanners
    Universite de Sherbrooke, Sherbrooke, Canada
    IEEE Trans Nucl Sci, 3 II (479-484):
  • [9] A novel APD-based detector module for multi-modality PET/SPECT/CT scanners
    Saoudi, A
    Lecomte, R
    IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1999, 46 (03) : 479 - 484
  • [10] The architecture of LabPET™, a small animal APD-based digital PET scanner
    Fontaine, Rejean
    Belanger, Francois
    Viscogliosi, Nicolas
    Semmaoui, Hicham
    Tetrault, Marc-Andre
    Michaud, Jean-Baptiste
    Pepin, Catherine
    Cadorette, Jules
    Lecomte, Roger
    2005 IEEE NUCLEAR SCIENCE SYMPOSIUM CONFERENCE RECORD, VOLS 1-5, 2005, : 2785 - 2789