Copper/Palladium Synergistic Catalysis for the syn- and anti-Selective Carboboration of Alkenes

被引：148

作者：

Logan, Kaitlyn M. ^{[1
]}

Smith, Kevin B. ^{[1
]}

Brown, M. Kevin ^{[1
]}

机构：

[1] Indiana Univ, Dept Chem, Bloomington, IN 47401 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2015年 / 54卷 / 17期

关键词：

carboboration; copper; cross-coupling; palladium; synergistic catalysis; CROSS-COUPLING REACTIONS; COPPER(I)-CATALYZED REACTION; ACTIVE CATALYST; ARYL; ALKYNES; STEREOCHEMISTRY; HALIDES; ESTERS; BIS(PINACOLATO)DIBORON; ELECTROPHILES;

D O I：

10.1002/anie.201500396

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A method for the diastereoselective carboboration of 1,2-disubstituted styrenes with aryl/vinyl bromides and (Bpin)(2) is reported. High diastereoselectivities and yields are observed for the formation of either diastereomer of the product from a single alkene isomer. These reactions provide access to a diverse range of structures from simple starting materials.

引用

页码：5228 / 5231

页数：4

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