A case report of nivolumab-induced myasthenia gravis and myositis in a metastatic renal cell carcinoma patient

被引：8

作者：

Nakanishi, Shotaro ^{[1
]}

Nishida, Sho ^{[1
]}

Miyazato, Minoru ^{[2
]}

Goya, Masato ^{[1
]}

Saito, Seiichi ^{[1
]}

机构：

[1] Univ Ryukyus, Grad Sch Med, Dept Urol, 207 Uehara, Nishihara, Okinawa 9030215, Japan

[2] Univ Ryukyus, Grad Sch Med, Dept Syst Physiol, Nishihara, Okinawa, Japan

来源：

UROLOGY CASE REPORTS | 2020年 / 29卷

关键词：

D O I：

10.1016/j.eucr.2019.101105

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We present a 78-year-old male with renal cell carcinoma who developed myasthenia gravis complicated by myositis after nivolumab administration, which was verified by the presence of antibodies against the acetylcholine receptor. The initial symptom was posterior neck pain, and biochemical examination of blood showed elevated levels of hepatic enzymes and creatine phosphokinase. The level of antibody against the acetylcholine receptor increased 4.1-fold. His condition progressed rapidly resulting in respiratory failure 15 days after conservative therapy.

引用

页数：2

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