Elevated high sensitivity CRP levels in patients with mitral stenosis and left atrial thrombus

被引：17

作者：

Karthikeyan, Ganesan ^{[2
]}

Thachil, Ajit ^{[2
]}

Sharma, Sanjeev ^{[2
]}

Kalaivani, M. ^{[1
]}

Ramakrishnan, Lakshmy ^{[3
]}

机构：

[1] All India Inst Med Sci, Dept Biostat, New Delhi 110029, India

[2] All India Inst Med Sci, Dept Cardiol, New Delhi 110029, India

[3] All India Inst Med Sci, Dept Cardiac Biochem, New Delhi 110029, India

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2007年 / 122卷 / 03期

关键词：

mitral stenosis; left atrial thrombus; high sensitivity C-reactive protein (hsCRP); homocysteine;

D O I：

10.1016/j.ijcard.2006.11.081

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Stasis of blood in the left atrium (LA) due to mitral obstruction is the principal mechanism of LA thrombus formation in patients with mitral stenosis (MS). The purpose of this case-control study was to determine the additional contributions of abnormal homosysteine/folate/B12 levels, chronic inflammation and markers of a procoagulant state. We found that elevated hsCRP levels were associated with the presence of left atrial thrombus, independent of the influence of conventional parameters indicating the severity of MS and its consequences. (C) 2007 Elsevier Ireland Ltd. All rights reserved.

引用

页码：252 / 254

页数：3

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