Click-Functionalized Compact Quantum Dots Protected by Multidentate-Imidazole Ligands: Conjugation-Ready Nanotags for Living-Virus Labeling and Imaging

被引:118
作者
Zhang, Pengfei [1 ]
Liu, Shuhui [1 ]
Gao, Duyang [1 ]
Hu, Dehong [1 ]
Gong, Ping [1 ]
Sheng, Zonghai [1 ]
Deng, Jizhe [1 ]
Ma, Yien [1 ]
Cai, Lintao [1 ]
机构
[1] Chinese Acad Sci, CAS Key Lab Hlth Informat, Inst Biomed & Biotechnol, Shenzhen Inst Adv Technol, Shenzhen 518055, Peoples R China
基金
中国国家自然科学基金;
关键词
SEMICONDUCTOR NANOCRYSTALS; CHEMISTRY; NANOPARTICLES; TRAFFICKING; INFECTION; CELLS; SHELL; SIZE;
D O I
10.1021/ja302367s
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We synthesized a new class of mutifunctional multidentate-imidazole polymer ligands by one-step reaction to produce conjugation-ready QDs with great stability and compact size. Furthermore, combined with strain-promoted click chemistry, we developed a general strategy for efficient labeling of living-viruses with QD probes.
引用
收藏
页码:8388 / 8391
页数:4
相关论文
共 42 条
[1]   Photochemical instability of CdSe nanocrystals coated by hydrophilic thiols [J].
Aldana, J ;
Wang, YA ;
Peng, XG .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (36) :8844-8850
[2]   Semiconductor Quantum Dots in Bioanalysis: Crossing the Valley of Death [J].
Algar, W. Russ ;
Susumu, Kimihiro ;
Delehanty, James B. ;
Medintz, Igor L. .
ANALYTICAL CHEMISTRY, 2011, 83 (23) :8826-8837
[3]   The Controlled Display of Biomolecules on Nanoparticles: A Challenge Suited to Bioorthogonal Chemistry [J].
Algar, W. Russ ;
Prasuhn, Duane E. ;
Stewart, Michael H. ;
Jennings, Travis L. ;
Blanco-Canosa, Juan B. ;
Dawson, Philip E. ;
Medintz, Igor L. .
BIOCONJUGATE CHEMISTRY, 2011, 22 (05) :825-858
[4]   Nanotechnology imaging probes: smaller and more stable [J].
Baker, Monya .
NATURE METHODS, 2010, 7 (12) :957-962
[5]   Copper-free click chemistry for dynamic in vivo imaging [J].
Baskin, Jeremy M. ;
Prescher, Jennifer A. ;
Laughlin, Scott T. ;
Agard, Nicholas J. ;
Chang, Pamela V. ;
Miller, Isaac A. ;
Lo, Anderson ;
Codelli, Julian A. ;
Bertozzi, Carolyn R. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (43) :16793-16797
[6]   Click Chemistry beyond Metal-Catalyzed Cycloaddition [J].
Becer, C. Remzi ;
Hoogenboom, Richard ;
Schubert, Ulrich S. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (27) :4900-4908
[7]   Progression of respiratory syncytial virus infection monitored by fluorescent quantum dot probes [J].
Bentzen, EL ;
House, F ;
Utley, TJ ;
Crowe, JE ;
Wright, DW .
NANO LETTERS, 2005, 5 (04) :591-595
[8]   Copper-Free Click Chemistry for Highly Luminescent Quantum Dot Conjugates: Application to in Vivo Metabolic Imaging [J].
Bernardin, Aude ;
Cazet, Aurelie ;
Guyon, Laurent ;
Delannoy, Philippe ;
Vinet, Francoise ;
Bonnaffe, David ;
Texier, Isabelle .
BIOCONJUGATE CHEMISTRY, 2010, 21 (04) :583-588
[9]   Virus trafficking - learning from single-virus tracking [J].
Brandenburg, Boerries ;
Zhuang, Xiaowei .
NATURE REVIEWS MICROBIOLOGY, 2007, 5 (03) :197-208
[10]   Bionanoconjugation via click chemistry: The creation of functional hybrids of lipases and gold nanoparticles [J].
Brennan, Jennifer L. ;
Hatzakis, Nikos S. ;
Tshikhudo, T. Robert ;
Dirvianskyte, Nijole ;
Razumas, Valdemaras ;
Patkar, Shamkant ;
Vind, Jesper ;
Svendsen, Allan ;
Nolte, Roeland J. M. ;
Rowan, Alan E. ;
Brust, Mathias .
BIOCONJUGATE CHEMISTRY, 2006, 17 (06) :1373-1375