Chiral calix[4]arenes bearing amino alcohol functionality as membrane carriers for transport of chiral amino acid methylesters and mandelic acid

被引：24

作者：

Bozkurt, Selahattin ^{[1
]}

Yilmaz, Mustafa ^{[1
]}

Sirit, Abdulkadir ^{[1
]}

机构：

[1] Selcuk Univ, Dept Chem, TR-42099 Konya, Turkey

来源：

CHIRALITY | 2012年 / 24卷 / 02期

关键词：

chiral calix[4]arene; bulk liquid membrane; amino acid methyl esters; mandelic acid; transport rate; BULK LIQUID-MEMBRANE; ENANTIOSELECTIVE TRANSPORT; ENANTIOMERIC RECOGNITION; SEPARATION; EXTRACTION; DERIVATIVES; RESOLUTION; PROPRANOLOL; CALIXARENES; POTASSIUM;

D O I：

10.1002/chir.21034

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Novel chiral calix[4]arene derivatives bearing amino alcohol moieties at the lower rim have been synthesized from the reaction of p-tert-butylcalix[4]arene diester with various amino alcohols. The transport of amino acid esters (phenylglycine, phenylalanine, and tryptophan methyl esters hydrochloride) and mandelic acid were studied through chloroform bulk liquid membrane system using chiral calix[4]arenes 15-20. All these receptors have been found to act as carriers for transport of aromatic amino acid methylesters and mandelic acid from the aqueous source phase to the aqueous receiving phase. The influence of calixarene and guest structures upon transport through liquid membrane is discussed. Chirality 24: 129-136, 2012. (c) 2011 Wiley Periodicals, Inc.

引用

页码：129 / 136

页数：8

共 55 条

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