Regulatory T cells and allergic asthma

被引：17

作者：

Yssel, H ^{[1
]}

Lécart, S ^{[1
]}

Pène, J ^{[1
]}

机构：

[1] CHU Arnaud Villeneuve, Inserm U454, F-34295 Montpellier 5, France

来源：

MICROBES AND INFECTION | 2001年 / 3卷 / 11期

关键词：

T regulatory cells; allergic asthma;

D O I：

10.1016/S1286-4579(01)01450-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Because of the characteristic airway inflammation observed in allergic asthma, the pathogenesis of this disease may be due, in part, to a lack of anti-inflammatory and immune suppressive mechanisms. Here, we discuss the possible involvement and therapeutic use of T regulatory cells and their soluble factors in this multifactorial disease. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

页码：899 / 904

页数：6

共 49 条

[1] Functional diversity of helper T lymphocytes [J].

Abbas, AK ;

Murphy, KM ;

Sher, A .

NATURE, 1996, 383 (6603) :787-793

[2] Role of interleukin 10 in specific immunotherapy [J].

Akdis, CA ;

Blesken, T ;

Akdis, M ;

Wüthrich, B ;

Blaser, K .

JOURNAL OF CLINICAL INVESTIGATION, 1998, 102 (01) :98-106

[3] Interleukin-10 regulation in normal subjects and patients with asthma [J].

Borish, L ;

Aarons, A ;

Rumbyrt, J ;

Cvietusa, P ;

Negri, J ;

Wenzel, S .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1996, 97 (06) :1288-1296

[4] INTERLEUKIN-10 (IL-10) INHIBITS THE RELEASE OF PROINFLAMMATORY CYTOKINES FROM HUMAN POLYMORPHONUCLEAR LEUKOCYTES - EVIDENCE FOR AN AUTOCRINE ROLE OF TUMOR-NECROSIS-FACTOR AND IL-1-BETA IN MEDIATING THE PRODUCTION OF IL-8 TRIGGERED BY LIPOPOLYSACCHARIDE [J].

CASSATELLA, MA ;

MEDA, L ;

BONORA, S ;

CESKA, M ;

CONSTANTIN, G .

JOURNAL OF EXPERIMENTAL MEDICINE, 1993, 178 (06) :2207-2211

[5] INTERLEUKIN-10 (IL-10) UP-REGULATES IL-1 RECEPTOR ANTAGONIST PRODUCTION FROM LIPOPOLYSACCHARIDE-STIMULATED HUMAN POLYMORPHONUCLEAR LEUKOCYTES BY DELAYING MESSENGER-RNA DEGRADATION [J].

CASSATELLA, MA ;

MEDA, L ;

GASPERINI, S ;

CALZETTI, F ;

BONORA, S .

JOURNAL OF EXPERIMENTAL MEDICINE, 1994, 179 (05) :1695-1699

[6] REGULATORY T-CELL CLONES INDUCED BY ORAL TOLERANCE - SUPPRESSION OF AUTOIMMUNE ENCEPHALOMYELITIS [J].

CHEN, YH ;

KUCHROO, VK ;

INOBE, J ;

HAFLER, DA ;

WEINER, HL .

SCIENCE, 1994, 265 (5176) :1237-1240

[7] Central role of immunoglobulin (Ig) E in the induction of lung eosinophil infiltration and T helper 2 cell cytokine production: Inhibition by a non-anaphylactogenic anti-IgE antibody [J].

Coyle, AJ ;

Wagner, K ;

Bertrand, C ;

Tsuyuki, S ;

Bews, J ;

Heusser, C .

JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 183 (04) :1303-1310

[8]

DE WMR, 1991, J EXP MED, V174, P1209

[9] Pretreatment with antibody to eosinophil major basic protein prevents hyperresponsiveness by protecting neuronal M-2 muscarinic receptors in antigen-challenged guinea pigs [J].

Evans, CM ;

Fryer, AD ;

Jacoby, DB ;

Gleich, GJ ;

Costello, RW .

JOURNAL OF CLINICAL INVESTIGATION, 1997, 100 (09) :2254-2262

[10] Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model [J].

Foster, PS ;

Hogan, SP ;

Ramsay, AJ ;

Matthaei, KI ;

Young, IG .

JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 183 (01) :195-201

← 1 2 3 4 5 →