Naturally-Derived Biomaterials for Tissue Engineering Applications

被引：80

作者：

Brovold, Matthew ^{[1
]}

Almeida, Joana I. ^{[2
]}

Pla-Palacin, Iris ^{[2
]}

Sainz-Arnal, Pilar ^{[2
,3
]}

Sanchez-Romero, Natalia ^{[2
]}

Rivas, Jesus J. ^{[2
]}

Almeida, Helen ^{[2
]}

Royo Dachary, Pablo ^{[4
,5
]}

Serrano-Aullo, Trinidad ^{[4
,5
]}

Soker, Shay ^{[1
]}

Baptista, Pedro M. ^{[4
,6
,7
,8
,9
]}

机构：

[1] Wake Forest Inst Regenerat Med, Winston Salem, NC 27101 USA

[2] Hlth Res Inst Aragon IIS Aragon, Zaragoza, Spain

[3] Aragon Hlth Sci Inst IACS, Zaragoza, Spain

[4] Inst Invest Sanitaria Aragon IIS Aragon, Zaragoza, Spain

[5] Lozano Blesa Univ Hosp, Dept Gastroenterol, Liver Transplant Unit, Zaragoza, Spain

[6] Ctr Biomed Res Network Liver & Digest Dis CIBEReh, Zaragoza, Spain

[7] Fdn Jimenez Diaz, Inst Invest Sanitaria, Madrid, Spain

[8] Univ Carlos III Madrid, Biomed & Aerosp Engn Dept, Madrid, Spain

[9] Fdn ARAID, Zaragoza, Spain

来源：

NOVEL BIOMATERIALS FOR REGENERATIVE MEDICINE | 2018年 / 1077卷

关键词：

Naturally-derived materials; Tissue decellularization; Tissue engineering; Protein-based biomaterials; Polysaccharide-based biomaterials; Glycosaminoglycans; Extracellular matrix-derived biomaterials; Solid organ bioengineering; Regulatory landscape for naturally-derived biomaterials; DONOR LIVER-TRANSPLANTATION; SMALL-INTESTINAL SUBMUCOSA; QT INTERVAL PROLONGATION; EMBRYONIC STEM-CELLS; FOR-SIZE SYNDROME; IN-VITRO; EXTRACELLULAR-MATRIX; REGENERATIVE MEDICINE; PRIMARY HEPATOCYTES; HEART-VALVES;

D O I：

10.1007/978-981-13-0947-2_23

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Naturally-derived biomaterials have been used for decades in multiple regenerative medicine applications. From the simplest cell microcarriers made of collagen or alginate, to highly complex decellularized whole-organ scaffolds, these biomaterials represent a class of substances that is usually first in choice at the time of electing a functional and useful biomaterial. Hence, in this chapter we describe the several naturally-derived biomaterials used in tissue engineering applications and their classification, based on composition. We will also describe some of the present uses of the generated tissues like drug discovery, developmental biology, bioprinting and transplantation.

引用

页码：421 / 449

页数：29

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