Small-diameter vascular graft prostheses: Current status

被引：108
|
作者：
Bos, GW
Poot, AA
Beugeling, T
van Aken, WG
Feijen, J
机构：
[1] Univ Twente, Fac Chem Technol, Sect Polymer Chem & Biomat, NL-7500 AE Enschede, Netherlands
[2] Univ Twente, Inst Biomed Technol, NL-7500 AE Enschede, Netherlands
来源：
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY | 1998年 / 106卷 / 02期
关键词：
atherosclerosis; endothelial cell seeding; growth factors; heparinization; review; small-diameter vascular grafts; tissue engineering; vascular graft sealants;
D O I：
10.1076/apab.106.2.100.4384
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In contrast to large-diameter vascular grafts (i.e. larger than 5 mm) which remain excellent for more than 10 years after implantation, small-diameter vascular grafts of both Dacron and Teflon occlude rapidly upon implantation. In this overview article, the strategies used to improve the patency of these small-diameter grafts, the current status in clinical trials, and further perspectives in the field of artificial vascular graft development are reviewed. It is concluded that, in view of recent developments in tissue engineering approaches, the future of small-diameter vascular prostheses looks promising.
引用
收藏
页码：100 / 115
页数：16
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