POLYSACCHARIDES FROM Fabaceae. V. α-GLUCAN FROM Sophora flavescens ROOTS

被引:9
作者
Olennikov, D. N. [1 ]
Stolbikova, A. V. [2 ]
Rokhin, A. V. [3 ]
Khobrakova, V. B. [1 ]
Tankhaeva, L. M. [1 ]
机构
[1] Russian Acad Sci, Siberian Branch, Inst Gen & Expt Biol, Ulan Ude 670047, Russia
[2] Russian Acad Sci, Siberian Branch, Siberian Inst Plant Physiol & Biochem, Irkutsk 664033, Russia
[3] Irkutsk State Univ, Irkutsk 664033, Russia
关键词
Sophora flavescens; Fabaceae; alpha-4,6-glucan; immunostimulating activity; LUPIN ALKALOIDS; CONSTITUENTS; FLAVONOIDS; AMYLOSE;
D O I
10.1007/s10600-011-9817-4
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Water-soluble polysaccharides from Sophora flavescens (Fabaceae) roots were studied. The dominant polymer SfP-1-1/2 of molecular weight 85 kDa was isolated using ion-exchange and gel chromatography. The structure of the isolated compound was alpha-(1 -> 4)-glucan partially substituted at the C-6 position by single glucopyranose units. A pharmacological study showed that SfP-1-1/2 exhibited under azathioprine suppression pronounced immunostimulating activity.
引用
收藏
页码:1 / 6
页数:6
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