Ga-67 scintigraphy in acute leukemia

被引:0
作者
Hod, N [1 ]
Pinkas, L
Volchek, Y
Horne, T
机构
[1] Assaf Harofe Med Ctr, Dept Nucl Med, IL-70300 Zerifin, Israel
[2] Assaf Harofe Med Ctr, Dept Hematol, IL-70300 Zerifin, Israel
[3] Tel Aviv Univ, Sackler Sch Med, IL-69978 Tel Aviv, Israel
关键词
acute leukemia; altered biodistribution; Ga-67; scintigraphy;
D O I
10.1097/00003072-200109000-00012
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
A 29-year-old woman had a 2-month history of increasing weakness and recurrent nose bleeding. Physical examination revealed no abnormalities except for mild splenomegaly. A blood count obtained at hospital admission revealed pancytopenia. Ga-67 imaging was performed using a large-field-of-view gamma camera and a medium-energy collimator 48 hours after the administration of 8 mCi Ga-67 citrate. The scan revealed a lack of normal Ga-67 biodistribution and generalized, diffusely increased osseous uptake of the radionuclide without focal abnormalities, consistent with the diagnosis of widespread bone marrow involvement by malignancy. Bone marrow biopsy showed massive replacement of normal cellular elements by acute lymphoblastic leukemia. This is an unusual case of altered biodistribution of Ga-67 mimicking a "normal" bone scan. This pattern should suggest the presence of an infiltrative marrow process.
引用
收藏
页码:785 / 786
页数:2
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