Relation of Neutrophil-to-Lymphocyte Ratio With GRACE Risk Score to In-Hospital Cardiac Events in Patients With ST-Segment Elevated Myocardial Infarction

被引：48

作者：

Oncel, Ramazan Can ^{[1
]}

Ucar, Mustafa ^{[1
]}

Karakas, Mustafa Serkan ^{[2
]}

Akdemir, Baris ^{[3
]}

Yanikoglu, Atakan ^{[1
]}

Gulcan, Ali Riza ^{[4
]}

Altekin, Refik Emre ^{[1
]}

Demir, Ibrahim ^{[1
]}

机构：

[1] Akdeniz Univ, Fac Med, Dept Cardiol, TR-07058 Antalya, Turkey

[2] Nigde State Hosp, Dept Cardiol, Nigde, Turkey

[3] Burdur State Hosp, Dept Cardiol, Burdur, Turkey

[4] Sanliurfa Res & Educ Hosp, Dept Cardiol, Sanliurfa, Turkey

来源：

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS | 2015年 / 21卷 / 04期

关键词：

GRACE risk score; inflammation; neutrophil-to-lymphocyte ratio; acute myocardial infarction; LONG-TERM MORTALITY; PERCUTANEOUS CORONARY INTERVENTION; NEUTROPHIL/LYMPHOCYTE RATIO; ANGIOGRAPHIC OUTCOMES; CARDIOVASCULAR RISK; PROGNOSTIC VALUE; PREDICTIVE-VALUE; ARTERY-DISEASE; HEART-FAILURE; ASSOCIATION;

D O I：

10.1177/1076029613505763

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In this study, we aimed to investigate the association of the neutrophil-to-lymphocyte ratio (NLR) with Global Registry of Acute Coronary Events (GRACE) risk score in patients with ST-segment elevated myocardial infarction (STEMI). We analyzed 101 consecutive patients with STEMI. Patients were divided into 3 groups by use of GRACE risk score. The association between NLR and GRACE risk score was assessed. The NLR showed a proportional increase correlated with GRACE risk score (P < .001). The occurrence of in-hospital cardiac death, reinfarction, or new-onset heart failure was significantly related to NLR at admission (P < .001). Likewise, NLR and GRACE risk score showed a significant positive correlation (r = .803, P < .001). In multivariate analysis, NLR resulted as a predictor of worse in-hospital outcomes independent of GRACE risk score. Our study suggests that the NLR is significantly associated with adverse in-hospital outcomes, independent of GRACE risk score in patients with STEMI.

引用

页码：383 / 388

页数：6

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