Synthesis and antiinflammatory activity of 1,3 disubstituted indolinones

被引:0
作者
Rajasekaran, A [1 ]
Mahesh, R
Parimoo, P
机构
[1] Periyar Coll Pharmaceut Sci Girls, Trichy 620021, India
[2] Birla Inst Technol & Sci, Pilani, Rajasthan, India
关键词
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
N-1-Benzyl-3-methylaminomethyl-2-indolinones (1) have been synthesized by Mannich reaction of N-1-benzyl-3-methyl-2-indolinone with different secondary amines. The synthesized compounds were evaluated for their antiinflammatory activity. Some of the compounds were found to possess promising antiinflammatory activity.
引用
收藏
页码:151 / 152
页数:2
相关论文
共 5 条
  • [1] CANAS A, 1972, J MED CHEM, V15, P763
  • [2] FRATER K, 1958, J AM CHEM SOC, V80, P983
  • [3] SINGH H, 1958, J PHARM PHARMACOL, V20, P316
  • [4] STUDIES WITH ANTIINFLAMMATORY OXINDOLECARBOXANILIDES
    WISEMAN, EH
    CHIAINI, J
    MCMANUS, JM
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (02) : 131 - 134
  • [5] 193235