Microwave-assisted synthesis of pyrrole-2-carboxamides

被引：13
|
作者：
Werner, S [1 ]
Iyer, PS [1 ]
机构：
[1] Univ Pittsburgh, Ctr Chem Methodol & Lib Dev UPCMLD, Pittsburgh, PA 15260 USA
来源：
SYNLETT | 2005年 / 09期
关键词：
heterocycles; library synthesis; microwave irradiation; Paal-Knorr reaction; pyrroles;
D O I：
10.1055/s-2005-868512
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A set of ten tricyclic pyrrole-2-carboxamides was synthesized by a Paal-Knorr cyclization under rapid and mild conditions using microwave irradiation. All compounds were also prepared using conventional heating techniques. An efficiency comparison of time, yield and effort clearly proved the microwave technique to be superior.
引用
收藏
页码：1405 / 1408
页数：4
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