Detection and Classification of Unannounced Physical Activities and Acute Psychological Stress Events for Interventions in Diabetes Treatment

Detection and classification of acute psychological stress (APS) and physical activity (PA) in daily lives of people with chronic diseases can provide precision medicine for the treatment of chronic conditions such as diabetes. This study investigates the classification of different types of APS and PA, along with their concurrent occurrences, using the same subset of feature maps via physiological variables measured by a wristband device. Random convolutional kernel transformation is used to extract a large number of feature maps from the biosignals measured by a wristband device (blood volume pulse, galvanic skin response, skin temperature, and 3D accelerometer signals). Three different feature selection techniques (principal component analysis, partial least squares- discriminant analysis (PLS-DA), and sequential forward selection) as well as four approaches for addressing imbalanced sizes of classes (upsampling, downsampling, adaptive synthetic sampling (ADASYN), and weighted training) are evaluated for maximizing detection and classification accuracy. A long short-term memory recurrent neural network model is trained to estimate PA (sedentary state, treadmill run, stationary bike) and APS (non-stress, emotional anxiety stress, mental stress) from wristband signals. The balanced accuracy scores for various combinations of data balancing and feature selection techniques range between 96.82% and 99.99%. The combination of PLS-DA for feature selection and ADASYN for data balancing provide the best overall performance. The detection and classification of APS and PA types along with their concurrent occurrences can provide precision medicine approaches for the treatment of diabetes.