Novel solid-phase synthetic method of sansalvarnide A

被引：0

作者：

Liu, SX ^{[1
]}

Feng, X

Geng, YL

Yao, J

Li, JZ

机构：

[1] Xian Jiaotong Univ, Coll Environm & Chem Engn, Xian 710049, Peoples R China

[2] Hebei Univ Sci & Technol, Coll Chem & Pharmaceut Engn, Shijiazhuang 050018, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 25卷 / 05期

关键词：

solid phase synthesis; silicon-linker; palladium catalyst; cyclic peptide; sansalvamide A;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

It was reported that butyldiethylsilane polystyrene reacted with N-Boc-4 bromophenylalaine under palladium catalyzation to directly form silicon-linker with silicon aryl carbon bond. The peptide was elongated by using Boc strategy. And sansalvamide A was obtained by solid phase synthesis using BOP (benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphate) as cyclization reagent.

引用

页码：604 / 607

页数：4

共 8 条

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