Tetrabutylammoniumbromide mediated Knoevenagel condensation in water: synthesis of cinnamic acids

被引:39
作者
Gupta, Monika [1 ]
Wakhloo, Basant Purnima
机构
[1] Univ Jammu, Dept Chem, Jammu 180006, India
[2] Reg Res Lab, NMR Instrumentat Sect, Jammu 180001, India
关键词
Knoevenagel condensation; carbonyl compounds; malonic acid; phase transfer catalyst; cinnamic acids; microwave activation;
D O I
10.3998/ark.5550190.0008.110
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A simple, mild and environment- friendly procedure has been developed for Knoevenagel condensation between aromatic aldehydes or ketones and malonic acid in the presence of tetrabutylammoniumbromide and K2CO3 under microwave irradiation in water. The products are obtained in excellent yields and are in a state of high purity.
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页码:94 / 98
页数:5
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