Histopathological and Immunohistochemical Study of the Prostatic Lesions

Benign nodular hyperplasia and adenocarcinoma are the most common diseases encountered in the aging population. Screening protocols and awareness programs over the years significantly reduced the morbidity and mortality. Chronic prostatitis is the commonest inflammatory condition associated with the benign lesions. Conventional adenocarcinoma forms the most common type of prostatic adenocarcinoma and is moderately to poorly differentiated, as graded by Gleason's microscopic grading. The present study was hypothesized that use Immunohistochemical marker p63 along with racemase marker may help to differentiate the benign from malignant prostatic lesions in diagnostically challenging cases effectively.