An overview of mycotoxin contamination in foods and its implications for human health

被引:314
作者
Reddy, K. R. N. [1 ]
Salleh, B. [1 ]
Saad, B. [1 ]
Abbas, H. K. [2 ]
Abel, C. A. [3 ]
Shier, W. T. [4 ]
机构
[1] Univ Sains Malaysia, Sch Biol & Chem Sci, Usm 11800, Penang, Malaysia
[2] ARS, USDA, Crop Genet Res Unit, Stoneville, MS 38776 USA
[3] Iowa State Univ, USDA, ARS, Corn Insects & Crop Genet Res Unit, Ames, IA USA
[4] Univ Minnesota, Coll Pharm, Dept Med Chem, Minneapolis, MN 55455 USA
关键词
Mycotoxins; foods; human health; aflatoxin; fumonisin; ZEA-MAYS HYBRIDS; NATURAL OCCURRENCE; OCHRATOXIN-A; AFLATOXIN B-1; FUMONISIN B-1; APPLE JUICE; FUSARIUM MYCOTOXINS; PATULIN PRODUCTION; LIVER-CANCER; FRUIT JUICES;
D O I
10.3109/15569541003598553
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
Mycotoxins are natural contaminants of cereals and other food commodities throughout the world and they significantly impact human and animal health. Mycotoxins are toxic secondary metabolites produced by species of filamentous fungi growing on grains before harvest and in storage. When ingested, inhaled, or absorbed through skin, mycotoxins may reduce appetite and general performance, and cause sickness or death in humans. Mycotoxins subject to government regulation in most countries include aflatoxins, fumonisins, ochratoxins, deoxynivalenol, zearalenone, and patulin, produced by species of Aspergillus, Fusarium, and Penicillium. Aflatoxins, fumonisins, and ochratoxins pose the most serious threats to human health worldwide. This review describes the prevalence of mycotoxins in foods and its implications on human health, which may help in establishing and carrying out proper management strategies. Data from detailed investigations of food mycotoxins worldwide help provide safer food for consumption and help prioritize future research programs.
引用
收藏
页码:3 / 26
页数:24
相关论文
共 318 条
[1]   Effet of temperature, rainfall and planting date on aflatoxin and fumonisin contamination, in commercial Bt and non-Bt-corn hybrids in Arkansas [J].
Abbas, Hamed K. ;
Shier, W. Thomas ;
Cartwright, Rick D. .
PHYTOPROTECTION, 2007, 88 (02) :41-50
[2]   MYCOTOXINS AND FUSARIUM SPP ASSOCIATED WITH INFECTED EARS OF CORN IN MINNESOTA [J].
ABBAS, HK ;
MIROCHA, CJ ;
MERONUCK, RA ;
POKORNY, JD ;
GOULD, SL ;
KOMMEDAHL, T .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1988, 54 (08) :1930-1933
[3]   Aflatoxin and fumonisin contamination of commercial corn (Zea mays) hybrids in Mississippi [J].
Abbas, HK ;
Williams, WP ;
Windham, GL ;
Pringle, HC ;
Xie, WP ;
Shier, WT .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2002, 50 (18) :5246-5254
[4]   Aflatoxin and fumonisin contamination of corn (maize, Zea mays) hybrids in Arkansas [J].
Abbas, HK ;
Cartwright, RD ;
Xie, WP ;
Shier, WT .
CROP PROTECTION, 2006, 25 (01) :1-9
[5]   Mycotoxin Production by Fusarium proliferatum isolates from rice with Fusarium sheath rot disease [J].
Abbas, HK ;
Cartwright, RD ;
Xie, W ;
Mirocha, CJ ;
Richard, JL ;
Dvorak, TJ ;
Sciumbato, GL ;
Shier, WT .
MYCOPATHOLOGIA, 1999, 147 (02) :97-104
[6]  
ABBAS HK, 2010, MYCOTOXIN PREVENTION
[7]   Mycotoxins in food products available in Qatar [J].
Abdulkadar, AHW ;
Al-Ali, AA ;
Al-Kildi, AM ;
Al-Jedah, JH .
FOOD CONTROL, 2004, 15 (07) :543-548
[8]   Survey of fungal counts and natural occurrence of aflatoxins in Malaysian starch-based foods [J].
Abdullah, N ;
Nawawi, A ;
Othman, I .
MYCOPATHOLOGIA, 1998, 143 (01) :53-58
[9]   Ochratoxin A and human chronic nephropathy in Tunisia: is the situation endemic? [J].
Abid, S ;
Hassen, W ;
Achour, A ;
Skhiri, H ;
Maaroufi, K ;
Ellouz, F ;
Creppy, E ;
Bacha, H .
HUMAN & EXPERIMENTAL TOXICOLOGY, 2003, 22 (02) :77-84
[10]   N-fatty acylation of hydrolyzed fumonisin B1, but not of intact fumonisin B1, strongly enhances in vitro mammalian toxicity [J].
Abou-Karam, M ;
Abbas, HK ;
Shier, WT .
JOURNAL OF TOXICOLOGY-TOXIN REVIEWS, 2004, 23 (01) :123-151