Rose bengal photocatalyzed Knoevenagel condensation of aldehydes and ketones in aqueous medium

被引：31

作者：

Das, Anupam ^{[1
]}

Thomas, K. R. Justin ^{[1
]}

机构：

[1] Indian Inst Technol Roorkee, Dept Chem, Organ Mat Lab, Roorkee 247667, Uttar Pradesh, India

来源：

GREEN CHEMISTRY | 2022年 / 24卷 / 12期

关键词：

EFFICIENT ROUTE; CATALYST-FREE; ONE-POT; OXIDATION; INDOLES; ACCESS; AMINES; GREEN; WATER;

D O I：

10.1039/d2gc01402e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Knoevenagel condensation is widely used in organic synthetic chemistry and several reaction conditions have been demonstrated. These reactions in neutral medium are challenging. In this report, we present a sustainable and greener method for Knoevenagel condensation reaction between carbonyl compounds (both aldehydes and ketones) and active methylene compounds using rose bengal as a photosensitizer in an aqueous medium. This protocol works smoothly for aromatic aldehydes and ketones containing both electron-donating and electron-withdrawing substituents.

引用

页码：4952 / 4957

页数：6

共 54 条

[1] Facile Synthesis of -Keto Sulfones Employing Fenton's Reagent in DMSO [J].

Chalikidi, Petrakis N. ;

Uchuskin, Maxim G. ;

Trushkov, Igor V. ;

Abaev, Vladimir T. ;

Serdyuk, Olga V. .

SYNLETT, 2018, 29 (05) :571-575

[2] One Robust Microporous TmIII-Organic Framework for Highly Catalytic Activity on Chemical CO2 Fixation and Knoevenagel Condensation [J].

Chen, Hongtai ;

Hu, Tuoping ;

Fan, Liming ;

Zhang, Xiutang .

INORGANIC CHEMISTRY, 2021, 60 (02) :1029-1037

[3] AIEE Active Nanoassemblies of Pyrazine Based Organic Photosensitizers as Efficient Metal-Free Supramolecular Photoredox Catalytic Systems [J].

Dadwal, Shruti ;

Deol, Harnimarta ;

Kumar, Manoj ;

Bhalla, Vandana .

SCIENTIFIC REPORTS, 2019, 9 (1) :11142

[4] Mechanism and free energy profile of base-catalyzed Knoevenagel condensation reaction [J].

Dalessandro, Ellen V. ;

Collin, Hugo P. ;

Valle, Marcelo S. ;

Pliego, Josefredo R., Jr. .

RSC ADVANCES, 2016, 6 (63) :57803-57810

[5] Knoevenagel Condensation of Aldehydes and Ketones with Malononitrile Catalyzed by Amine Compounds-Tethered Fe3O4@SiO2 Nanoparticles [J].

de Resende Filho, Joao Batista M. ;

Pires, Gilvan P. ;

Gomes de Oliveira Ferreira, Joao Marcos ;

Teotonio, Ercules E. S. ;

Vale, Juliana A. .

CATALYSIS LETTERS, 2017, 147 (01) :167-180

[6]

Dehkordi M.F., 2019, J REP PHARM SCI, V5, P80

[7]

Eibner A., 1911, Chem-ZTG, V35, P753

[8] In vitro anticancer activity of pyrano[3, 2-c]chromene derivatives with both cell cycle arrest and apoptosis induction [J].

El-Agrody, Ahmed M. ;

Fouda, Ahmed M. ;

Assiri, Mohammed A. ;

Mora, Ahmed ;

Ali, Tarik E. ;

Alam, Mohammed M. ;

Alfaifi, Mohammad Y. .

MEDICINAL CHEMISTRY RESEARCH, 2020, 29 (04) :617-629

[9]

FILIMONOV VN, 1964, DOKL AKAD NAUK SSSR+, V154, P922

[10] The role of renewables in the energy crisis [J].

Fracastoro, GianVincenzo .

SCIENCE AND THE FUTURE, 2014, 2

← 1 2 3 4 5 6 →