Molecular evidences on anti-inflammatory, anticancer, and memory-boosting effects of frankincense

被引:19
作者
Khajehdehi, Mina [1 ]
Khalaj-Kondori, Mohammad [1 ]
Baradaran, Behzad [2 ]
机构
[1] Univ Tabriz, Fac Nat Sci, Dept Anim Biol, Tabriz, Iran
[2] Tabriz Univ Med Sci, Immunol Res Ctr, Tabriz, Iran
关键词
boswellic acid; cancer; frankincense; inflammation; memory improvement; nutraceutical; SERRATA GUM RESIN; INTESTINAL ADENOMATOUS POLYPOSIS; ACID INDUCES APOPTOSIS; BETA-BOSWELLIC ACID; CELL-CYCLE ARREST; ACETYL-11-KETO-BETA-BOSWELLIC ACID; COLORECTAL-CANCER; OXIDATIVE STRESS; NATURAL-PRODUCTS; COGNITIVE IMPAIRMENT;
D O I
10.1002/ptr.7399
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Chemical diversity of natural products with drug-like features has attracted much attention from medicine to develop more safe and effective drugs. Their anti-inflammatory, antitumor, analgesic, and other therapeutic properties are sometimes more successful than chemical drugs in controlling disease due to fewer drug resistance and side effects and being more tolerable in a long time. Frankincense, the oleo gum resin extracted from the Boswellia species, contains some of these chemicals. The anti-inflammatory effect of its main ingredient, boswellic acid, has been traditionally used to treat many diseases, mainly those target memory functions. In this review, we have accumulated research evidence from the beneficial effect of Frankincense consumption in memory improvement and the prevention of inflammation and cancer. Besides, we have discussed the molecular pathways mediating the therapeutic effects of this natural supplement.
引用
收藏
页码:1194 / 1215
页数:22
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