Novel Influenza D virus: Epidemiology, pathology, evolution and biological characteristics

被引:105
作者
Su, Shuo [1 ,2 ]
Fu, Xinliang [3 ,4 ]
Li, Gairu [1 ,2 ]
Kerlin, Fiona [5 ]
Veit, Michael [5 ]
机构
[1] Nanjing Agr Univ, Inst Immunol, Jiangsu Engn Lab Anim Immunol, Nanjing, Jiangsu, Peoples R China
[2] Nanjing Agr Univ, Coll Vet Med, Nanjing, Jiangsu, Peoples R China
[3] South China Agr Univ, Key Lab Zoonosis Prevent & Control Guangdong Pro, Guangzhou, Guangdong, Peoples R China
[4] South China Agr Univ, Coll Vet Med, Guangzhou, Guangdong, Peoples R China
[5] Free Univ Berlin, Vet Fac, Ctr Infect Med, Inst Virol, Berlin, Germany
关键词
bovine; cattle; epidemiology; evolution; HEF; Influenzavirus D; pathology; zoonosis; C-VIRUS; A VIRUS; B VIRUS; SEROLOGICAL EVIDENCE; RESPIRATORY-DISEASE; HEMAGGLUTININ; CATTLE; INFECTION; RNA; TRANSMISSION;
D O I
10.1080/21505594.2017.1365216
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In 2011, a new virus was isolated from pigs with influenza-like symptoms and subsequently also from cattle, which are the main reservoir of the virus. It is similar to Influenza C virus (ICV), a (predominantly) human pathogen, causing respiratory disease in children. Since the virus is unable to reassort with ICV (and based on several other criteria as discussed in the text) it is now officially named as Influenzavirus D (IDV), a new genus of the Orthomyxoviridae. We summarize the epidemiology, pathology and evolution of IDV and its biological characteristics with emphasis on the only glycoprotein HEF. Based on the limited data available we finally consider whether IDV represent a public health threat.
引用
收藏
页码:1580 / 1591
页数:12
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