Delayed fingolimod-associated asystole

被引:59
作者
Espinosa, Patricio S. [1 ]
Berger, Joseph R. [2 ]
机构
[1] N Oaks Neurol, Hammond, LA 70403 USA
[2] Univ Kentucky, Dept Neurol, Lexington, KY 40536 USA
关键词
asystole; cardiac conduction; fingolimod; heart; risperidone; RELAPSING MULTIPLE-SCLEROSIS; RISPERIDONE THERAPY; ORAL FINGOLIMOD;
D O I
10.1177/1352458511410344
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Oral fingolimod (Gilenya) is a sphingosine-1-phosphate-receptor modulator that prevents the egress of lymphocytes from lymph nodes. Fingolimod reduces relapses and delays disability progression in patients with relapsing forms of multiple sclerosis (MS). We report a patient with MS who developed asystole and sustained bradycardia 21 hours after the first dose of fingolimod.
引用
收藏
页码:1387 / 1389
页数:3
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