Beat-to-beat QT interval variability in children: normal and physiologic data

被引:14
作者
Kusuki, Hirofumi [1 ,2 ]
Kuriki, Marina [2 ]
Horio, Kayo [2 ]
Hosoi, Misa [3 ]
Matsuura, Hideaki [3 ]
Fujino, Masayuki [4 ]
Eryu, Yoshihiko [4 ]
Miyata, Masafumi [4 ]
Yasuda, Toshiaki [5 ]
Yamazaki, Toshio [4 ]
Nagaoka, Shunji [2 ]
Hata, Tadayoshi [2 ,4 ]
机构
[1] Mie Univ Hosp, Clin Lab, Tsu, Mie, Japan
[2] Fujita Hlth Univ, Grad Sch Hlth Sci, Toyoake, Aichi, Japan
[3] Fujita Hlth Univ Hosp, Clin Lab, Toyoake, Aichi, Japan
[4] Fujita Hlth Univ, Dept Pediat, Toyoake, Aichi, Japan
[5] Aichi Childrens Hlth & Med Ctr, Dept Cardiol, Aichi, Japan
关键词
QT variability index (QTVI); Standard growth curve; Standard value; Sex difference; Prepubescent; REPOLARIZATION LABILITY; VENTRICULAR REPOLARIZATION; CARDIOMYOPATHY; AGE;
D O I
10.1016/j.jelectrocard.2010.07.016
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: QT interval variability provides information on ventricular vulnerability. However, QT interval variability in children has not been adequately evaluated. Methods: One hundred seventy-three consecutive nursing infants and children (male-female, 106:67) up to school age with no intrinsic cardiac disease were included in this study, and they were categorized into 6 age-related groups. The QT variability index (QTVI) was calculated based on an electrocardiogram; and age-specific standard values, sex-specific classification, and a standard growth curve covering 0 to 7 years were constructed. Results: The QTVI decreased in an age-dependent manner, reached constant values after school age, and exhibited no sex-specific differences in 6 age-related groups. Conclusions: Based on the age-dependent standardized QTVI values, it is possible to estimate the instability of ventricular repolarization in pediatric patients with better accuracy. (c) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:326 / 329
页数:4
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