Calcium silicate/calcium aluminate composite biocement for bone restorative application: synthesis, characterisation and in vitro biocompatibility

被引：12
作者：
Tan, Y. [1 ]
Liu, Y. [1 ]
Birdi, G. [2 ]
Grover, L. M. [2 ]
Li, H. [1 ]
Li, K. [1 ]
机构：
[1] Cent S Univ, State Key Lab Powder Met, Changsha 410083, Hunan, Peoples R China
[2] Univ Birmingham, Sch Chem Engn, Birmingham B15 2TT, W Midlands, England
来源：
ADVANCES IN APPLIED CERAMICS | 2016年 / 115卷 / 07期
基金：
中国国家自然科学基金;
关键词：
Hydration; Mechanical properties; Calcium silicate cement; Calcium aluminate cement; Composite; Inorganic bone cement; LITHIUM-FLUORIDE; PHOSPHATE CEMENT; MALEIC-ACID; HYDROXYAPATITE; BIOACTIVITY; STRENGTH; SILICA; BEHAVIOR; POROSITY; ROUTE;
D O I：
10.1080/17436753.2016.1163006
中图分类号：
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Pure beta-dicalcium silicate and monocalcium aluminate powder were prepared by Pechini method. A series of calcium silicate/calcium aluminate cements (CSC/CAC) were prepared. The setting time, crystalline phases, microstructures, compressive strength, cells attachment and silicon release of the cements were investigated. The results indicate that the setting time of CSC/CAC was shorter than that of either CSC or CAC. The hydration products in CSC/CAC composite are gehlenite (Ca2Al2SiO7 center dot 8H(2)O), calcium aluminate hydrate (Ca(3)Al(2)O(6)xH(2)O), and katoite (Ca2Al2O6 center dot 6H(2)O). Platelike crystals were found in the microstructure. The liquid to powder ratio has a significant effect on the porosity and the strength of CSC/CAC. The MC3T3 cells attached well to the surfaces of CSC/CAC. However, the cells proliferation on the surface of 7S3A was better than that of 3S7A due to its higher silicon release. In general, CSC/CAC exhibits good biocompatibility and relative high strength, and may be suitable for some non-load bearing bone restorative applications.
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页码：384 / 390
页数：7
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