Determination of atropine and scopolamine by proton nuclear magnetic resonance spectroscopy

被引：0
|
作者：
Naqvi, AA [1 ]
Mandal, S [1 ]
Verma, RK [1 ]
机构：
[1] Cent Inst Med & Aromat Plants, Lucknow 226015, Uttar Pradesh, India
来源：
PHYTOCHEMICAL ANALYSIS | 1998年 / 9卷 / 04期
关键词：
atropine; scopolamine; Hyoscyamus muticus; Datura metel; quantitative nuclear magnetic resonance spectroscopy;
D O I：
10.1002/(SICI)1099-1565(199807/08)9:4<168::AID-PCA408>3.0.CO;2-Q
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A simple, accurate and specific proton nuclear magnetic resonance spectrometric method is described for the quantitative determination of atropine and scopolamine in plants. The method is based on a comparison of the integrated peak areas of the N-CH3 protons of both compounds (centred at 2.15 and 2.5 ppm) with that of the sharp singlet of 1, 4-dioxane (positioned at 3.5 ppm) which is used as the internal standard. (C) 1998 John Wiley & Sons, Ltd.
引用
收藏
页码：168 / 170
页数：3
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