Radical scavenging activity of methanol leaf extracts of Orthosiphon stamineus

被引：19

作者：

Akowuah, GA ^{[1
]}

Zhari, I ^{[1
]}

Norhayati, I ^{[1
]}

Sadikun, A ^{[1
]}

机构：

[1] Univ Sains Malaysia, Sch Pharmaceut Sci, Herbal Secretariat, Minden 11800, Penang, Malaysia

来源：

PHARMACEUTICAL BIOLOGY | 2004年 / 42卷 / 08期

关键词：

antioxidants; free-radical scavenging; Orthosiphon stainineus; superoxide anion;

D O I：

10.1080/13880200490902572

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The antioxidant activity of methanol extracts of Orthosiphon stamineus Benth (Lamiaceae), cultivated in different regions of Malaysia, was determined by measuring the scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and on superoxide anion. The results showed a variation in free-radical and superoxide-anion scavenging activities of the methanol extracts ranging from 62.82 to 92.34% and 53.29 to 75.88%, respectively. Methanol extract was active, and its antioxidative potency was comparable to that of pure quercetin and higher than that of the widely used synthetic antioxidant butylated hydroxylanisole (BHA). The UV and HPLC chromatographic fingerprints of the major phenolics were qualitatively similar for all the methanol leaf extracts of Orthosiphon stamineus from various locations.

引用

页码：629 / 635

页数：7

共 22 条

[1] SUPEROXIDE AND SINGLET OXYGEN IN MILK LIPID PEROXIDATION [J].

AURAND, LW ;

BOONE, NH ;

GIDDINGS, GG .

JOURNAL OF DAIRY SCIENCE, 1977, 60 (03) :363-369

[2]

CUVELIER ME, 1996, J AM OIL CHEM SOC, V73, P654

[3]

DECKER EA, 1995, NUTR REV, V53, P49, DOI 10.1111/j.1753-4887.1995.tb01502.x

[4]

EVANS CA, 1996, BIOCHEM SOC T, V24, P790

[5] EFFECTS OF GENERATION OF SUPEROXIDE ANION ON PERMEABILITY OF LIPOSOMES [J].

GOLDSTEIN, IM ;

WEISSMANN, G .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 75 (03) :604-609

[6] High molecular weight plant polyphenolics (tannins) as biological antioxidants [J].

Hagerman, AE ;

Riedl, KM ;

Jones, GA ;

Sovik, KN ;

Ritchard, NT ;

Hartzfeld, PW ;

Riechel, TL .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1998, 46 (05) :1887-1892

[7]

Hatano T, 1988, CHEM PHARM BULL, V36, P1090, DOI DOI 10.1248/CPB.36.2090

[8]

Hegnauer R., 1966, CHEMOTAXONOMIE PFLAN, VIV, P314

[9] FLAVONOID INTAKE AND LONG-TERM RISK OF CORONARY-HEART-DISEASE AND CANCER IN THE 7 COUNTRIES STUDY [J].

HERTOG, MGL ;

KROMHOUT, D ;

ARAVANIS, C ;

BLACKBURN, H ;

BUZINA, R ;

FIDANZA, F ;

GIAMPAOLI, S ;

JANSEN, A ;

MENOTTI, A ;

NEDELJKOVIC, S ;

PEKKARINEN, M ;

SIMIC, BS ;

TOSHIMA, H ;

FESKENS, EJM ;

HOLLMAN, PCH ;

KATAN, MB .

ARCHIVES OF INTERNAL MEDICINE, 1995, 155 (04) :381-386

[10] ONE-ELECTRON TRANSFER REDOX POTENTIALS OF FREE-RADICALS .1. OXYGEN-SUPEROXIDE SYSTEM [J].

ILAN, YA ;

CZAPSKI, G ;

MEISEL, D .

BIOCHIMICA ET BIOPHYSICA ACTA, 1976, 430 (02) :209-224

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