Nano-sized silica supported FeCl3 as an efficient heterogeneous catalyst for the synthesis of 1,2,4-triazine derivatives

被引：6

作者：

Habibi, Davood ^{[1
]}

Vakili, Somayyeh ^{[1
]}

机构：

[1] Bu Ali Sina Univ, Fac Chem, Dept Organ Chem, Hamadan 6517838683, Iran

来源：

CHINESE JOURNAL OF CATALYSIS | 2015年 / 36卷 / 04期

关键词：

Nano-sized silica supported FeCl3; Multicomponent reactions; 1,2,4-Triazines; alpha; beta-Dicarbonyl compounds; Semicarbazide; Thiosemicarbazide; ONE-POT SYNTHESIS; SOLVENT-FREE SYNTHESIS; 1,2,4,5-TETRASUBSTITUTED IMIDAZOLES; TETRASUBSTITUTED IMIDAZOLES; ANTITUMOR-ACTIVITY; ANALOGS; ACID; SYSTEM;

D O I：

10.1016/S1872-2067(15)60829-4

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The one-pot synthesis of a series of 1,2,4-triazines from the reactions of semicarbazide or thiosemicarbazide with various alpha,beta-dicarbonyl compounds under reflux conditions in a EtOH-H2O (9:1) mixture as solvent and catalyzed by nano-sized silica supported FeCl3 (FeCl3@SiO2) was investigated. The FeCl3 content of the catalyst was measured by atomic absorption to get the adsorption capacity. The reactions gave high yields of the product and the catalyst was easily separated and reused for successive reaction runs without significant loss of activity. (C) 2015, Dalian Institute of Chemical Physics, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.

引用

收藏

页码：620 / 625

页数：6

相关论文

共 25 条

[1]

Ahmed Gamal A, 2002, Boll Chim Farm, V141, P438

[2] Photocatalytic activity of ZnO impregnated Hβ and mechanical mix of ZnO/Hβ in the degradation of monocrotophos in aqueous solution [J].

Anandan, S. ;

Vinu, A. ;

Venkatachalam, N. ;

Arabindoo, B. ;

Murugesan, V. .

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2006, 256 (1-2) :312-320

[3] Nano TiO2-supported Preyssler-type heteropolyacid (nanoTiO2/H14[NaP5W30O110]): an efficient and re-usable catalyst for the one-pot synthesis of N-acetyl-2-aryl-1,2-dihydro-(4H)-3,1-benzoxazin-4-ones [J].

Azarifar, Davood ;

Khatami, Seyed-Mola ;

Zolfigol, Mohammad Ali ;

Sheikh, Davood .

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2013, 10 (05) :1039-1046

[4] The use of benzil to obtain functionalized N-heterocycles [J].

Braibante, Mara E. E. ;

Braibante, Hugo T. S. ;

Uliana, Marciana R. ;

Costa, Carla C. ;

Spenazzatto, Marcelo .

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2008, 19 (05) :909-913

[5] Silica gel/FeCl3:: An efficient and recyclable heterogenous catalyst for one step synthesis of 4(3H)-quinazolinones under solvent free conditions [J].

Chari, M. Adharvana ;

Shobha, D. ;

Mukkanti, K. .

CATALYSIS COMMUNICATIONS, 2006, 7 (10) :787-790

[6] Silica gel/NaHSo4 catalyzed one-pot synthesis of Hantzsch 1,4-dihydropyridines at ambient temperature [J].

Chari, MA ;

Syamasundar, K .

CATALYSIS COMMUNICATIONS, 2005, 6 (09) :624-626

[7] Efficient synthesis of purine analogues:: an FeCl3-SiO2-promoted cyclization reaction of 4,5-diaminopyrimidines with aldehydes leading to 6,8,9-trisubstituted purines [J].

Dang, Q ;

Brown, BS ;

Erion, MD .

TETRAHEDRON LETTERS, 2000, 41 (34) :6559-6562

[8] Synthetic approach to 6-benzoyl-2H-[1,2,4] triazine-3,5-dione and 6-benzyl-5-thioxo-3,4-dihydro-2h-[1,2,4] triazin-3-one and studies on their transformation to fused [1,2,4]triazine systems [J].

El Massry, AM .

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2003, 178 (05) :1143-1155

[9] Novel quinazolone derivatives as antitumor agents [J].

Ghorab, MM ;

Abdel-Hamide, SG ;

El-Sayed, SM .

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 1998, 142 :57-68

[10] Synthesis of some new thiadiazole selena, triazine, thiazole and cyanopyridine derivatives with assay for their antitumor activity [J].

Ghorab, MM ;

AbdelHamide, SG ;

Zeid, MMA .

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 1996, 112 (1-4) :7-17