Fibrillar superstructure from extended nanotapes formed by a collagen-stimulating peptide

被引:66
作者
Castelletto, Valeria [1 ]
Hamley, Ian W. [1 ,5 ]
Perez, Javier [2 ]
Abezgauz, Ludmila [3 ,4 ]
Danino, Dganit [3 ,4 ]
机构
[1] Univ Reading, Dept Chem, Reading RG6 6AD, Berks, England
[2] Beamline SWING, Synchrotron Soleil, F-91190 St Aubin, France
[3] Technion Israel Inst Technol, Dept Food Engn & Biotechnol, IL-32000 Haifa, Israel
[4] Technion Israel Inst Technol, Russell Berrie Nanotechnol Inst, IL-32000 Haifa, Israel
[5] Harwell Sci & Innovat Campus, Diamond Light Source, Didcot OX11 0DE, Oxon, England
基金
英国工程与自然科学研究理事会;
关键词
MOLECULAR ARCHITECTURE; AMPHIPHILE NANOFIBERS; POLYPEPTIDES; LIPOPEPTIDE; SURFACTANT; PROTEINS; LAMELLAR; PHASES;
D O I
10.1039/c0cc03793a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The nanostructure of a peptide amphiphile in commercial use in anti-wrinkle creams is investigated. The peptide contains a matrikine, collagen-stimulating, pentapeptide sequence. Self-assembly into giant nanotapes is observed and the internal structure was found to comprise bilayers parallel to the flat tape surfaces.
引用
收藏
页码:9185 / 9187
页数:3
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