Can a Two-Step Process Be an Effective Monoclonal Antibody Purification Platform?

被引：0
作者：
Duong, Phu [1 ]
机构：
[1] Tosoh Biosci, Proc Media, Tokyo, Japan
来源：
BIOPHARM INTERNATIONAL | 2020年 / 33卷 / 11期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Protein A affinity chromatography is widely used for the capture of monoclonal antibodies (mAbs) and other Fc-containing biotherapeutic drugs. In recent years, more mAbs have been developed and produced to address the high demand for treating diseases. Downstream processing for mAb purification is responsible for up to 80% of the entire production costs of biotherapeutics. To reduce the cost of manufacturing for biological therapeutics, streamlining downstream processing is a necessity for chromatographers and process engineers. BioPharm International recently sat down with Dr. Phu Duong, Product Manager of Process Media, Tosoh Bioscience, to discuss the effectiveness of a two-step process for mAb purification.
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页码：36 / 37
页数：2
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