It's all about sex: gender, lung development and lung disease

被引：297
作者：
Carey, Michelle A. [1 ]
Card, Jeffrey W. [1 ]
Voltz, James W. [1 ]
Arbes, Samuel J., Jr. [1 ]
Germolec, Dori R. [1 ]
Korach, Kenneth S. [1 ]
Zeldin, Darryl C. [1 ]
机构：
[1] NIEHS, NIH, Res Triangle Pk, NC 27709 USA
来源：
TRENDS IN ENDOCRINOLOGY AND METABOLISM | 2007年 / 18卷 / 08期
关键词：
D O I：
10.1016/j.tem.2007.08.003
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Accumulating evidence suggests that gender affects the incidence, susceptibility and severity of several lung diseases. Gender also influences lung development and physiology. Data from both human and animal studies indicate that sex hormones might contribute to disease pathogenesis or serve as protective factors, depending on the disease involved. In this review, the influence of gender and sex hormones on lung development and pathology will be discussed, with specific emphasis on pulmonary fibrosis, asthma and cancer.
引用
收藏
页码：308 / 313
页数：6
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