Reproductive toxicity in boron exposed workers in Bandirma, Turkey

被引：29
作者：
Basaran, Nursen [1 ]
Duydu, Yalcin [2 ]
Bolt, Hermann M. [3 ]
机构：
[1] Hacettepe Univ, Fac Pharm, Dept Toxicol, TR-06100 Ankara, Turkey
[2] Ankara Univ, Fac Pharm, Dept Toxicol, TR-06100 Ankara, Turkey
[3] Leibniz Res Ctr Working Environm & Human Factors, D-44139 Dortmund, Germany
来源：
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY | 2012年 / 26卷 / 2-3期
关键词：
Boric acid; Occupational exposure; Biological monitoring; Drinking water; Semen; Blood; INVITRO FERTILIZATION; DNA INTEGRITY; COMET ASSAY; SPERM;
D O I：
10.1016/j.jtemb.2012.04.013
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Boric acid and sodium borates have been considered as being "toxic to reproduction and development", following results of animal studies with high doses. However unfavorable effects of boron exposure on reproduction and development have not been proved in epidemiological studies so far. The aim of the present study was to investigate the reproductive toxicity indicators in highly exposed workers employed in a boric acid production plant in Bandirma, Turkey. Two hundred and four workers participated in this study. The mean blood boron concentration of the high exposure group of workers was 223.89 +/- 69.49 (152.82-454.02) ng/g. Unfavorable effects of boron exposure on the reproductive toxicity indicators were not observed. (C) 2012 Elsevier GmbH. All rights reserved.
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收藏
页码：165 / 167
页数：3
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